KNOSD_ORYSJ
ID KNOSD_ORYSJ Reviewed; 374 AA.
AC Q0J6N4; P93423; P93424; P94016; Q7DN84; Q84YX8;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2009, sequence version 2.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Homeobox protein knotted-1-like 13;
DE AltName: Full=Homeobox protein OSH45;
GN Name=OSH45; OrderedLocusNames=Os08g0292900, LOC_Os08g19650;
GN ORFNames=OJ1705_A03.8, OSJNBb0075O18.121;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1; 2 AND 3), FUNCTION, TISSUE
RP SPECIFICITY, AND ALTERNATIVE SPLICING.
RC STRAIN=cv. Nipponbare;
RX PubMed=7599652; DOI=10.1046/j.1365-313x.1995.07060927.x;
RA Tamaoki M., Tsugawa H., Minami E., Kayano T., Yamamoto N.,
RA Kano-Murakami Y., Matsuoka M.;
RT "Alternative RNA products from a rice homeobox gene.";
RL Plant J. 7:927-938(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18430022; DOI=10.1111/j.1742-4658.2008.06424.x;
RA Jain M., Tyagi A.K., Khurana J.P.;
RT "Genome-wide identification, classification, evolutionary expansion and
RT expression analyses of homeobox genes in rice.";
RL FEBS J. 275:2845-2861(2008).
CC -!- FUNCTION: Isoform 3 acts as transcription activator, but isoforms 1 and
CC 2 do not. {ECO:0000269|PubMed:7599652}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1; Synonyms=OSH44;
CC IsoId=Q0J6N4-1; Sequence=Displayed;
CC Name=2; Synonyms=OSH45;
CC IsoId=Q0J6N4-2; Sequence=VSP_036190;
CC Name=3; Synonyms=OSH42;
CC IsoId=Q0J6N4-3; Sequence=VSP_036189, VSP_036191, VSP_036192;
CC -!- TISSUE SPECIFICITY: Isoforms 1 and 2 are expressed in roots, stems,
CC shoot meristem, leaf blades, leaf sheaths and flowers. Isoform 3 is
CC expressed in stems, shoot meristem, rachis, leaf blades and leaf
CC sheaths. {ECO:0000269|PubMed:7599652}.
CC -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC {ECO:0000255|PROSITE-ProRule:PRU00559}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC57787.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD01204.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF23381.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; D49704; BAA08552.1; -; Genomic_DNA.
DR EMBL; D49704; BAA08553.1; -; Genomic_DNA.
DR EMBL; D49704; BAA08554.1; -; Genomic_DNA.
DR EMBL; AP003918; BAD01204.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP005390; BAC57787.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008214; BAF23381.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; T03874; T03874.
DR PIR; T03875; T03875.
DR AlphaFoldDB; Q0J6N4; -.
DR SMR; Q0J6N4; -.
DR STRING; 4530.OS08T0292900-01; -.
DR PaxDb; Q0J6N4; -.
DR PRIDE; Q0J6N4; -.
DR eggNOG; KOG0773; Eukaryota.
DR InParanoid; Q0J6N4; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR005540; KNOX1.
DR InterPro; IPR005541; KNOX2.
DR Pfam; PF03789; ELK; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF03790; KNOX1; 1.
DR Pfam; PF03791; KNOX2; 1.
DR SMART; SM01188; ELK; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM01255; KNOX1; 1.
DR SMART; SM01256; KNOX2; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51213; ELK; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..374
FT /note="Homeobox protein knotted-1-like 13"
FT /id="PRO_0000360017"
FT DOMAIN 270..290
FT /note="ELK"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00559"
FT DNA_BIND 291..354
FT /note="Homeobox; TALE-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 214..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..196
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_036189"
FT VAR_SEQ 367..374
FT /note="SNAGDNNS -> RAGGIHPKQ (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036190"
FT VAR_SEQ 367
FT /note="S -> R (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_036191"
FT VAR_SEQ 368..374
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_036192"
SQ SEQUENCE 374 AA; 39767 MW; 66975384F3268001 CRC64;
MAFHGHLPHE MTMQALGADD AAVAAAAAAG GVGAGGAPAW MRYNDGSFLH LQTTSDSSAS
PSGAAAAAAA AAAAAAAGVQ QWMGGGGGGE DAVAAAMGGG GEADAARCKA EILAHPLYEQ
LLSAHVACLR IATPVDQLPR IDAQLAQSQG VVAKYSALAA AAAGDDGREL DQFMTHYVLL
LCSFKEQLQQ HVRVHAMEAV MACWELEQNL QSLTGASPGE GTGATMSDGE DDQADSEANM
YDPSLDGADN MGFGLPTESE RSLMERVRQE LKHELKQGYK EKLIDIREEI LRKRRAGKLP
GDTTSTLKAW WQSHAKWPYP TEEDKARLVQ ETGLQLKQIN NWFINQRKRN WHSNPSSSTS
VKTKRKSNAG DNNS
