ID   KNOX8_MAIZE             Reviewed;          85 AA.
AC   P56666;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Homeobox protein knotted-1-like 8;
DE   Flags: Fragment;
GN   Name=KNOX8;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Ear of corn, and Seedling;
RX   PubMed=7866030; DOI=10.2307/3869914;
RA   Kerstetter R., Vollbrecht E., Lowe B., Veit B., Yamaguchi J., Hake S.;
RT   "Sequence analysis and expression patterns divide the Maize knotted1-like
RT   homeobox genes into two classes.";
RL   Plant Cell 6:1877-1887(1994).
CC   -!- FUNCTION: Probably binds to the DNA sequence 5'-TGAC-3'.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Strongly expressed in ear inflorescence primordia
CC       and shoot meristem. Weakly expressed in embryos. Absent from leaves.
CC   -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00559}.
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DR   AlphaFoldDB; P56666; -.
DR   SMR; P56666; -.
DR   STRING; 4577.GRMZM2G135447_P01; -.
DR   PaxDb; P56666; -.
DR   PRIDE; P56666; -.
DR   eggNOG; KOG0773; Eukaryota.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; P56666; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR005539; ELK_dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   Pfam; PF03789; ELK; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   SMART; SM01188; ELK; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS51213; ELK; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           <1..>85
FT                   /note="Homeobox protein knotted-1-like 8"
FT                   /id="PRO_0000048969"
FT   DOMAIN          1..21
FT                   /note="ELK"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00559"
FT   DNA_BIND        22..85
FT                   /note="Homeobox; TALE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   NON_TER         1
FT   NON_TER         85
SQ   SEQUENCE   85 AA;  10370 MW;  080D4CC3B5CC9E50 CRC64;
     ELKHQLLRKY GGYLGGLRQE FSKRKKKGKL PKEARQKLLH WWELHYKWPY PSETEKMALA
     ETTGLDPKQI NNWFINQRKR HWKPA