ID   KORB1_ECOLX             Reviewed;         349 AA.
AC   Q52313; P71174;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Transcriptional repressor protein KorB;
GN   Name=korB;
OS   Escherichia coli.
OG   Plasmid IncP-beta R751.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Macartney D.P., Williams D.R., Stafford T., Foster A., Thomas C.M.;
RT   "Evolution of the partitioning and global regulation functions of the IncP
RT   central control region.";
RL   Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: In conjunction with KorA, inhibits the transcription of the
CC       kilA, trfA and korAB operons. Is also involved in the negative control
CC       of the kilB operon.
CC   -!- SIMILARITY: Belongs to the ParB family. {ECO:0000305}.
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DR   EMBL; U67194; AAC64419.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q52313; -.
DR   SMR; Q52313; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.730; -; 1.
DR   Gene3D; 2.30.30.150; -; 1.
DR   InterPro; IPR010575; KorB_C.
DR   InterPro; IPR037048; KorB_C_sf.
DR   InterPro; IPR042075; KorB_DNA-db.
DR   InterPro; IPR013741; KorB_domain.
DR   InterPro; IPR004437; ParB/RepB/Spo0J.
DR   InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR   InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR   InterPro; IPR008988; Transcriptional_repressor_C.
DR   Pfam; PF08535; KorB; 1.
DR   Pfam; PF06613; KorB_C; 1.
DR   Pfam; PF02195; ParBc; 1.
DR   SMART; SM00470; ParB; 1.
DR   SUPFAM; SSF110849; SSF110849; 1.
DR   SUPFAM; SSF50037; SSF50037; 1.
DR   TIGRFAMs; TIGR00180; parB_part; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Plasmid; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..349
FT                   /note="Transcriptional repressor protein KorB"
FT                   /id="PRO_0000178698"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          246..296
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..296
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   349 AA;  38125 MW;  61A5871B755BBA76 CRC64;
     MSAKTNAKKK EQDKPQSSGL GLDGLGDLAG LLNEQPAANA GGAGPQELPL DLIDEDPHQP
     RTADNPGFSP ESIAEIGETI KARGVKSPIS VRENPDAPGR YLINHGARRY RGSKWAHKTT
     IPAFIDNDYN EADQVIENLQ RNELTAREIA DFIGRELAKG KKKGEIAKEI GKSPAFVTQH
     VTLLDLPEPI AEAFNSGRGK DVTVINELVT AYKKNPDEVA AWLADDSQEL TRGSVKLLRE
     FLEDKRSHDD GDRDPNTVDA LTGKTDAEAG DGEQGPQDDD AKGKKEPKEA DPDKLKKAII
     QVKHDDRPAR LILNRRPPAE GWAWLKYEDD GQEFEADLGT VQLVALLEG