ID   KORB_METJA              Reviewed;         270 AA.
AC   Q57957;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=2-oxoglutarate synthase subunit KorB;
DE            EC=1.2.7.3;
DE   AltName: Full=2-ketoglutarate oxidoreductase beta chain;
DE            Short=KOR;
DE   AltName: Full=2-oxoglutarate-ferredoxin oxidoreductase subunit beta;
GN   Name=korB; OrderedLocusNames=MJ0537;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2
CC         + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA;
CC         Xref=Rhea:RHEA:17297, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:16810,
CC         ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57292; EC=1.2.7.3;
CC   -!- SUBUNIT: Heterotetramer of the KorA, KorB, KorC and KorD subunits.
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DR   EMBL; L77117; AAB98531.1; -; Genomic_DNA.
DR   PIR; A64367; A64367.
DR   RefSeq; WP_010870041.1; NC_000909.1.
DR   AlphaFoldDB; Q57957; -.
DR   SMR; Q57957; -.
DR   STRING; 243232.MJ_0537; -.
DR   DNASU; 1451402; -.
DR   EnsemblBacteria; AAB98531; AAB98531; MJ_0537.
DR   GeneID; 1451402; -.
DR   KEGG; mja:MJ_0537; -.
DR   eggNOG; arCOG01599; Archaea.
DR   HOGENOM; CLU_048564_2_0_2; -.
DR   InParanoid; Q57957; -.
DR   OMA; SAWIASP; -.
DR   OrthoDB; 43666at2157; -.
DR   PhylomeDB; Q57957; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme-bd_C.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; SSF52518; 1.
PE   4: Predicted;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..270
FT                   /note="2-oxoglutarate synthase subunit KorB"
FT                   /id="PRO_0000099942"
SQ   SEQUENCE   270 AA;  29895 MW;  4F7331CF37216554 CRC64;
     MHPALKYMRQ DRLPHIFCSG CGNGIVMNCF LKAIEELNIK PEDYIAVSGI GCSSRVPGYL
     YCDSLHTTHG RPIAFATGIK IARPDKHVVV FTGDGDLAAI GGNHFIHGCR RNIDLTVICI
     NNNIYGMTGG QVSPTTPYGK KATTAPYGSI ENTMDLCKMA IAAGATYVAR WTTAHPIQLV
     RSIKKGIQKK GFAFIEVVSQ CPTYYGRFNI SRKPADMIKF LKENSIHLNK AKDMSEEELN
     GKIVVGEFLD IEKPEFVEEL HKLIEKLKSE