ID   KORB_METTH              Reviewed;         286 AA.
AC   O27113;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=2-oxoglutarate synthase subunit KorB;
DE            EC=1.2.7.3;
DE   AltName: Full=2-ketoglutarate oxidoreductase beta chain;
DE            Short=KOR;
DE   AltName: Full=2-oxoglutarate-ferredoxin oxidoreductase subunit beta;
GN   Name=korB; OrderedLocusNames=MTH_1034;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2
CC         + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA;
CC         Xref=Rhea:RHEA:17297, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:16810,
CC         ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57292; EC=1.2.7.3;
CC   -!- SUBUNIT: Heterotetramer of the KorA, KorB, KorC and KorD subunits.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000666; AAB85530.1; -; Genomic_DNA.
DR   PIR; A69005; A69005.
DR   RefSeq; WP_010876665.1; NC_000916.1.
DR   AlphaFoldDB; O27113; -.
DR   SMR; O27113; -.
DR   STRING; 187420.MTH_1034; -.
DR   EnsemblBacteria; AAB85530; AAB85530; MTH_1034.
DR   GeneID; 1471442; -.
DR   KEGG; mth:MTH_1034; -.
DR   PATRIC; fig|187420.15.peg.1017; -.
DR   HOGENOM; CLU_048564_2_0_2; -.
DR   OMA; SAWIASP; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme-bd_C.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; SSF52518; 1.
PE   4: Predicted;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..286
FT                   /note="2-oxoglutarate synthase subunit KorB"
FT                   /id="PRO_0000099943"
SQ   SEQUENCE   286 AA;  31475 MW;  DB72DBF53B1C8D45 CRC64;
     MEKRENPYLR YLRRERLPHI FCAGCGNGIV LNSFFKGMEM AGIDFDNIAM VSGIGCSSRI
     PGYVNCDSLH TTHGRPISFA TGLKLGNPSL DVVVFTGDGD AAAIGGNHLI HGARRNIDMT
     VICINNSIYG MTGGQISPTF PEGSYGSTAP YGALEDPFDL AELVTAAGAS YVARWTTAHP
     LQLANSIKKG LKNRGFSFIE AISQCPTYFG RKNRMRSPVE MMRFMKENSL NRRKALKMEP
     DEVEGKIIVG EFANRPQPEL CEKICSMVDE KSGRALDMIR SAYRDD