ID   KPPR1_CUPNH             Reviewed;         292 AA.
AC   P19924;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Phosphoribulokinase, plasmid;
DE            Short=PRK;
DE            Short=PRKase;
DE            EC=2.7.1.19;
DE   AltName: Full=Phosphopentokinase;
GN   Name=cfxP; Synonyms=cbbPP; OrderedLocusNames=PHG421;
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OG   Plasmid megaplasmid pHG1.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2559876; DOI=10.1016/0378-1119(89)90490-3;
RA   Kossmann J., Klintworth R., Bowien B.;
RT   "Sequence analysis of the chromosomal and plasmid genes encoding
RT   phosphoribulokinase from Alcaligenes eutrophus.";
RL   Gene 85:247-252(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=12948488; DOI=10.1016/s0022-2836(03)00894-5;
RA   Schwartz E., Henne A., Cramm R., Eitinger T., Friedrich B., Gottschalk G.;
RT   "Complete nucleotide sequence of pHG1: a Ralstonia eutropha H16 megaplasmid
RT   encoding key enzymes of H(2)-based lithoautotrophy and anaerobiosis.";
RL   J. Mol. Biol. 332:369-383(2003).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-18.
RX   PubMed=2997141; DOI=10.1128/jb.164.2.954-956.1985;
RA   Klintworth R., Husemann M., Salnikow J., Bowien B.;
RT   "Chromosomal and plasmid locations for phosphoribulokinase genes in
RT   Alcaligenes eutrophus.";
RL   J. Bacteriol. 164:954-956(1985).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-
CC         bisphosphate + H(+); Xref=Rhea:RHEA:19365, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:57870, ChEBI:CHEBI:58121,
CC         ChEBI:CHEBI:456216; EC=2.7.1.19;
CC   -!- PATHWAY: Carbohydrate biosynthesis; Calvin cycle.
CC   -!- SUBUNIT: Homooctamer.
CC   -!- SIMILARITY: Belongs to the phosphoribulokinase family. {ECO:0000305}.
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DR   EMBL; M33562; AAA21957.1; -; Genomic_DNA.
DR   EMBL; AY305378; AAP86170.1; -; Genomic_DNA.
DR   PIR; JQ0400; JQ0400.
DR   RefSeq; WP_011154333.1; NZ_CP039289.1.
DR   AlphaFoldDB; P19924; -.
DR   SMR; P19924; -.
DR   STRING; 381666.PHG421; -.
DR   EnsemblBacteria; AAP86170; AAP86170; PHG421.
DR   GeneID; 39976769; -.
DR   KEGG; reh:PHG421; -.
DR   PATRIC; fig|381666.6.peg.349; -.
DR   eggNOG; COG3954; Bacteria.
DR   HOGENOM; CLU_962223_0_0_4; -.
DR   OMA; HYIHAED; -.
DR   OrthoDB; 1793376at2; -.
DR   UniPathway; UPA00116; -.
DR   Proteomes; UP000008210; Plasmid megaplasmid pHG1.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008974; F:phosphoribulokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0019253; P:reductive pentose-phosphate cycle; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006082; PRK.
DR   InterPro; IPR006083; PRK/URK.
DR   Pfam; PF00485; PRK; 1.
DR   PRINTS; PR00478; PHRIBLKINASE.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00567; PHOSPHORIBULOKINASE; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Calvin cycle; Direct protein sequencing; Kinase;
KW   Nucleotide-binding; Plasmid; Reference proteome; Transferase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:2997141"
FT   CHAIN           2..292
FT                   /note="Phosphoribulokinase, plasmid"
FT                   /id="PRO_0000201950"
FT   BINDING         12..20
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   292 AA;  33161 MW;  045FAC49329F5BC9 CRC64;
     MSERYPIIAI TGSSGAGTTS VTRTFENIFC REGVKSVVIE GDSFHRYDRA EMKVKMAEAE
     RTGNMNFSHF GAENNLFGDL ESLFRSYAES GTGMRRRYLH STEEAAPFGQ QPGTFTAWEP
     LPADTDLLFY EGLHGGVVTD EVNVAQYPNL LIGVVPVINL EWIQKLWRDK KQRGYSTEAV
     TDTILRRMPD YVNYICPQFS RTHVNFQRVP CVDTSNPFIS REIPAPDESM VVIRFANPKG
     IDFQYLLSMI HDSFMSRANT IVVPGGKMEL AMQLIFTPFV LRMMERRKRA AL