ID   KPPR2_CUPNH             Reviewed;         292 AA.
AC   P19923; Q0K1E6;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Phosphoribulokinase, chromosomal;
DE            Short=PRK;
DE            Short=PRKase;
DE            EC=2.7.1.19;
DE   AltName: Full=Phosphopentokinase;
GN   Name=cfxP; OrderedLocusNames=H16_B1389;
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2559876; DOI=10.1016/0378-1119(89)90490-3;
RA   Kossmann J., Klintworth R., Bowien B.;
RT   "Sequence analysis of the chromosomal and plasmid genes encoding
RT   phosphoribulokinase from Alcaligenes eutrophus.";
RL   Gene 85:247-252(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=16964242; DOI=10.1038/nbt1244;
RA   Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA   Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I.,
RA   Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT   "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT   eutropha H16.";
RL   Nat. Biotechnol. 24:1257-1262(2006).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-18.
RX   PubMed=2997141; DOI=10.1128/jb.164.2.954-956.1985;
RA   Klintworth R., Husemann M., Salnikow J., Bowien B.;
RT   "Chromosomal and plasmid locations for phosphoribulokinase genes in
RT   Alcaligenes eutrophus.";
RL   J. Bacteriol. 164:954-956(1985).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-
CC         bisphosphate + H(+); Xref=Rhea:RHEA:19365, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:57870, ChEBI:CHEBI:58121,
CC         ChEBI:CHEBI:456216; EC=2.7.1.19;
CC   -!- PATHWAY: Carbohydrate biosynthesis; Calvin cycle.
CC   -!- SUBUNIT: Homooctamer.
CC   -!- SIMILARITY: Belongs to the phosphoribulokinase family. {ECO:0000305}.
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DR   EMBL; M33563; AAA21959.1; -; Genomic_DNA.
DR   EMBL; AM260480; CAJ96178.1; -; Genomic_DNA.
DR   PIR; JQ0399; JQ0399.
DR   RefSeq; WP_010809295.1; NZ_CP039288.1.
DR   AlphaFoldDB; P19923; -.
DR   SMR; P19923; -.
DR   STRING; 381666.H16_B1389; -.
DR   PRIDE; P19923; -.
DR   EnsemblBacteria; CAJ96178; CAJ96178; H16_B1389.
DR   GeneID; 57647287; -.
DR   KEGG; reh:H16_B1389; -.
DR   eggNOG; COG3954; Bacteria.
DR   HOGENOM; CLU_962223_0_0_4; -.
DR   OMA; TDILFYE; -.
DR   OrthoDB; 1793376at2; -.
DR   UniPathway; UPA00116; -.
DR   Proteomes; UP000008210; Chromosome 2.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008974; F:phosphoribulokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0019253; P:reductive pentose-phosphate cycle; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006082; PRK.
DR   InterPro; IPR006083; PRK/URK.
DR   Pfam; PF00485; PRK; 1.
DR   PRINTS; PR00478; PHRIBLKINASE.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00567; PHOSPHORIBULOKINASE; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Calvin cycle; Direct protein sequencing; Kinase;
KW   Nucleotide-binding; Reference proteome; Transferase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:2997141"
FT   CHAIN           2..292
FT                   /note="Phosphoribulokinase, chromosomal"
FT                   /id="PRO_0000201951"
FT   BINDING         12..20
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   292 AA;  33316 MW;  7707185622E4ED5A CRC64;
     MSERYPIIAI TGSSGAGTTS VTRTFENIFR REGVKSVVIE GDSFHRYDRA EMKVKMAEAE
     RTGNMNFSHF GEENNLFGEL ENLFRSYAET GTGMHRHYLH SPEEAAPFGQ EPGTFTQWEP
     LPADTDLLFY EGLHGGVVTD SVNVAQYPNL LIGVVPVINL EWIQKLWRDK KQRGYSTEAV
     TDTILRRMPD YVNYICPQFS RTHVNFQRVP CVDTSNPFIS REIPAPDESM VVIRFANPKG
     IDFQYLLSMI HDSFMSRANT IVVPGGKMEL AMQLIFTPFV LRMMERRKRA AQ