ID   KPRB_CHICK              Reviewed;         369 AA.
AC   Q5ZL26;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 2;
DE            Short=PRPP synthase-associated protein 2;
GN   Name=PRPSAP2; ORFNames=RCJMB04_8b17;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Seems to play a negative regulatory role in 5-phosphoribose
CC       1-diphosphate synthesis. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family.
CC       {ECO:0000305}.
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DR   EMBL; AJ719908; CAG31567.1; -; mRNA.
DR   RefSeq; NP_001006165.1; NM_001006165.1.
DR   AlphaFoldDB; Q5ZL26; -.
DR   SMR; Q5ZL26; -.
DR   STRING; 9031.ENSGALP00000008105; -.
DR   PaxDb; Q5ZL26; -.
DR   GeneID; 416521; -.
DR   KEGG; gga:416521; -.
DR   CTD; 5636; -.
DR   VEuPathDB; HostDB:geneid_416521; -.
DR   eggNOG; KOG1503; Eukaryota.
DR   InParanoid; Q5ZL26; -.
DR   OrthoDB; 1043963at2759; -.
DR   PhylomeDB; Q5ZL26; -.
DR   PRO; PR:Q5ZL26; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0002189; C:ribose phosphate diphosphokinase complex; IBA:GO_Central.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IBA:GO_Central.
DR   GO; GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IBA:GO_Central.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.2020; -; 2.
DR   InterPro; IPR029099; Pribosyltran_N.
DR   InterPro; IPR029057; PRTase-like.
DR   InterPro; IPR005946; Rib-P_diPkinase.
DR   PANTHER; PTHR10210; PTHR10210; 1.
DR   Pfam; PF14572; Pribosyl_synth; 1.
DR   Pfam; PF13793; Pribosyltran_N; 1.
DR   SUPFAM; SSF53271; SSF53271; 2.
DR   TIGRFAMs; TIGR01251; ribP_PPkin; 1.
PE   2: Evidence at transcript level;
KW   Nucleotide biosynthesis; Reference proteome.
FT   CHAIN           1..369
FT                   /note="Phosphoribosyl pyrophosphate synthase-associated
FT                   protein 2"
FT                   /id="PRO_0000366927"
SQ   SEQUENCE   369 AA;  40804 MW;  15394B0D9FDF51B2 CRC64;
     MFCVPSTETG AIMNITKGGL VLFSANSNSS CMELSKRIAE RLGVEMGKVQ VYQEPNRETR
     VQIQESVRGK DVFIIQTVSK DVNTTIMELL IMVYACKTSC AKSIIGVIPY FPYSKQCKMR
     KRGSIVSKLL ASMMCKAGLT HLITMDLHQK EIQGFFNIPV DNLRASPFLL QYIQEEIPDY
     RNAVIVAKSP ASAKRAQSFA ERLRLGIAVI HGEAQDAESD MVDGRHSPPT AKNVAAIHRS
     LEIPMLIPKE KPPITVVGDV GGRIAIIVDD IIDDVDSFLA AAETLKERGA YKIFVMATHG
     LLSSDAPRLI EESAIDEVVV TNTIPHEIQK LQCPKIKTVD ISMILSEAIR RIHNGESMSY
     LFRNIGLDD