ARAR_ALKHC
ID ARAR_ALKHC Reviewed; 375 AA.
AC Q9KBQ0;
DT 26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Arabinose metabolism transcriptional repressor;
GN Name=araR; OrderedLocusNames=BH1875;
OS Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS / JCM 9153 / C-125) (Bacillus halodurans).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=272558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
CC -!- FUNCTION: Transcriptional repressor of the arabinose utilization genes.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR EMBL; BA000004; BAB05594.1; -; Genomic_DNA.
DR PIR; C83884; C83884.
DR RefSeq; WP_010898036.1; NC_002570.2.
DR AlphaFoldDB; Q9KBQ0; -.
DR SMR; Q9KBQ0; -.
DR STRING; 272558.10174493; -.
DR PRIDE; Q9KBQ0; -.
DR EnsemblBacteria; BAB05594; BAB05594; BAB05594.
DR KEGG; bha:BH1875; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_15_0_9; -.
DR OMA; DYIFPRI; -.
DR OrthoDB; 1796334at2; -.
DR Proteomes; UP000001258; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01541; PBP1_AraR; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR033532; AraR_ligand_bind_dom.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00392; GntR; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..375
FT /note="Arabinose metabolism transcriptional repressor"
FT /id="PRO_0000050618"
FT DOMAIN 1..70
FT /note="HTH gntR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT DNA_BIND 30..49
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ SEQUENCE 375 AA; 42747 MW; 4D20C954C6A95867 CRC64;
METKYNFVKQ QIKSKILEGI VLPHGKIGSE NELMKEYNVS RHTVRKAIDE LVNEGWVYRK
QGAGTFCADR TDQKNPIGKA QRKNIALITT YLSEYIFPSI IRGAESILSE HGYQVTIFST
NNNHEQEKRA LEAVLSQRFD GLIVEPTKSS IPNPNINYYL NLERQGIPYV MINAYYEELE
PYFLGMDDVK GGYTQTKHLL DLGHEQIVGL FKNDDLQGAK RLKGFIKAHR ERGIALNPQH
IITYTTEQKN AKPLEELHRI FKDRSHRPTG IVCYNDELAL KLLDVIREFD IRVPEELSVV
GYDDSFLSVA SEVKLTTIQH PKVEMGIDAA KLIISCIEQE RKDRSADGEQ SIIYEPKLVV
RHSTAEAKSE KGVAK