ID   KPSD1_ECOLX             Reviewed;         558 AA.
AC   Q03961;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Polysialic acid transport protein KpsD;
DE   Flags: Precursor;
GN   Name=kpsD;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=K1;
RX   PubMed=8021185; DOI=10.1128/jb.176.13.4025-4033.1994;
RA   Wunder D.E., Aaronson W., Hayes S.F., Bliss J.M., Silver R.P.;
RT   "Nucleotide sequence and mutational analysis of the gene encoding KpsD, a
RT   periplasmic protein involved in transport of polysialic acid in Escherichia
RT   coli K1.";
RL   J. Bacteriol. 176:4025-4033(1994).
CC   -!- FUNCTION: Involved in the translocation of the polysialic acid capsule
CC       across the outer membrane to the cell surface. May function as the
CC       periplasmic binding element of the PSA transport system, in which it
CC       transiently interacts with the membrane component of the transporter,
CC       binds polysaccharide and transports the polymer to a component in the
CC       outer membrane.
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- SIMILARITY: To E.coli K5 KpsD. {ECO:0000305}.
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DR   EMBL; M64977; AAA21682.1; -; Genomic_DNA.
DR   PIR; I41324; I41324.
DR   RefSeq; WP_001331697.1; NZ_WVVR01000003.1.
DR   AlphaFoldDB; Q03961; -.
DR   SMR; Q03961; -.
DR   TCDB; 1.B.18.1.2; the outer membrane auxiliary (oma) protein family.
DR   OMA; DRREFNY; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003715; Poly_export.
DR   InterPro; IPR019554; Soluble_ligand-bd.
DR   Pfam; PF02563; Poly_export; 1.
DR   Pfam; PF10531; SLBB; 1.
PE   1: Evidence at protein level;
KW   Capsule biogenesis/degradation; Direct protein sequencing; Periplasm;
KW   Signal; Transport.
FT   SIGNAL          1..20
FT   CHAIN           21..558
FT                   /note="Polysialic acid transport protein KpsD"
FT                   /id="PRO_0000021558"
SQ   SEQUENCE   558 AA;  60371 MW;  CDB8F0CE4E89D828 CRC64;
     MKLFKSILLI AACHAAQASA AIDINADPNL TGAAPLTGIL NGQQSDTQNM SGFDNTPPPS
     PPVVMSRMFG AQLFNGTSAD SGATVGFNPD YILNPGDSIQ VRLWGAFTFD GALQVDPKGN
     IFLPNVGPVK VAGVSNSQLN ALVTSKVKEV YQSNVNVYAS LLQAQPVKVY VTGFVRNPGL
     YGGVTSDSLL NYLIKAGGVD PERGSYVDIV VKRGNRVRSN VNLYDFLLNG KLGLSQFADG
     DTIIVGPRQH TFSVQGDVFN SYDFEFRESS IPVTEALSWA RPKPGATHIT IMRKQGLQKR
     SEYYPISSAP GRMLQNGDTL IVSTDRYAGT IQVRVEGAHS GEHAMVLPYG STMRAVLEKV
     RPNSMSQMNA VQLYRPSVAQ RQKEMLNLSL QKLEEASLSA QSSTKEEASL RMQEAQLISR
     FVAKARTVVP KGEVILNESN IDSVLLEDGD VINIPEKTSL VMVHGEVLFP NAVSWQKGMT
     TEDYIEKCGG LTQKSGNARI IVIRQNGAAV NAEDVDSLKP GDEIMVLPKY ESKNIEVTRG
     ISTILYQLAV GAKVILSL