ID   KPSD5_ECOLX             Reviewed;         558 AA.
AC   P42213;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Polysialic acid transport protein KpsD;
DE   Flags: Precursor;
GN   Name=kpsD;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K5;
RX   PubMed=8397187; DOI=10.1128/jb.175.18.5978-5983.1993;
RA   Pazzani C., Rosenow C., Boulnois G.J., Bronner D., Jann K., Roberts I.S.;
RT   "Molecular analysis of region 1 of the Escherichia coli K5 antigen gene
RT   cluster: a region encoding proteins involved in cell surface expression of
RT   capsular polysaccharide.";
RL   J. Bacteriol. 175:5978-5983(1993).
CC   -!- FUNCTION: Involved in the translocation of the polysialic acid capsule
CC       across the outer membrane to the cell surface. May function as the
CC       periplasmic binding element of the PSA transport system, in which it
CC       transiently interacts with the membrane component of the transporter,
CC       binds polysaccharide and transports the polymer to a component in the
CC       outer membrane.
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- SIMILARITY: To E.coli K1 KpsD. {ECO:0000305}.
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DR   EMBL; X74567; CAA52656.1; -; Genomic_DNA.
DR   PIR; B48492; B48492.
DR   AlphaFoldDB; P42213; -.
DR   SMR; P42213; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003715; Poly_export.
DR   InterPro; IPR019554; Soluble_ligand-bd.
DR   Pfam; PF02563; Poly_export; 1.
DR   Pfam; PF10531; SLBB; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Periplasm; Signal; Transport.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000250"
FT   CHAIN           21..558
FT                   /note="Polysialic acid transport protein KpsD"
FT                   /id="PRO_0000021559"
SQ   SEQUENCE   558 AA;  60484 MW;  999FB9628F6FAB53 CRC64;
     MKLFKSILLI AACHAAQASA TIDINADPNL TGAAPLTGIL NGQKSDTQNM SGFDNTPPPA
     PPVVMSRMFG AQLFNGTSAD SGATVGFNPD YILNPGDSIQ VRLWGAFTFD GALQVDPKGN
     IFLPNVGPVK IAGVSNSQLN ALVTSKVKEV YQSNVNVYAS LLQAQPVKVY VTGFVRNPGL
     YGGVTSDSLL NYLIKAGGVD PERGSYVDIV VKRGNRVRSN VNLYDFLLNG KLGLSQFADG
     DTIIVGPRQH TFSVQGDVFN SYDFEFRESS IPVTEALSWA RPKPGATHIT IMRKQGLQKR
     SEYYPISSAP GRMLQNGDTL IVSTDRYAGT IQVRVEGAHS GEHAMVLPYG STMRAVLEKV
     RPNSMSQMNA VQLYRPSVAQ RQKEMLNLSL QKLEEASLSA QSSTKEEASL RMQEAQLISR
     FVAKARTVVP KGEVILNESN IDSVLLEDGD VINIPEKTSL VMVHGEVLFP NAVSWQKGMT
     TEDYIEKCGG LTQKSGNARI IVIRQNGARV NAEDVDSLKP GDEIMVLPKY ESKNIEVTRG
     ISTILYQLAV GAKVILSL