ID   KPSE_ECOL6              Reviewed;         382 AA.
AC   P62587; P42214;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Capsule polysaccharide export inner-membrane protein KpsE;
GN   Name=kpsE; OrderedLocusNames=c3687;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Involved in the translocation of the polysialic acid capsule.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BexC/CtrB/KpsE family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN82135.1; -; Genomic_DNA.
DR   RefSeq; WP_000905920.1; NC_004431.1.
DR   AlphaFoldDB; P62587; -.
DR   SMR; P62587; -.
DR   STRING; 199310.c3687; -.
DR   EnsemblBacteria; AAN82135; AAN82135; c3687.
DR   KEGG; ecc:c3687; -.
DR   eggNOG; COG3524; Bacteria.
DR   HOGENOM; CLU_027864_2_0_6; -.
DR   OMA; LYMAFIA; -.
DR   BioCyc; ECOL199310:C3687-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0009276; C:Gram-negative-bacterium-type cell wall; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR   GO; GO:0015774; P:polysaccharide transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005705; BexC_CtrB_KpsE_VexD.
DR   TIGRFAMs; TIGR01010; BexC_CtrB_KpsE; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Cell inner membrane; Cell membrane;
KW   Membrane; Polysaccharide transport; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..382
FT                   /note="Capsule polysaccharide export inner-membrane protein
FT                   KpsE"
FT                   /id="PRO_0000084318"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   382 AA;  43045 MW;  44E9508484DC05B2 CRC64;
     MLIKVKSAVS WMRARLSAIS LADIQKHLAK IIILAPMAVL LIYLAIFSQP RYMSESKVAI
     KRSDDLNSGS LNFGLLLGAS NPSSAEDALY LKEYINSPDM LAALDKQLNF REAFSHSGLD
     FLNHLSKDET AEGFLKYYKD RINVSYDDKT GLLNIQTQGF SPEFALKFNQ TVLKESERFI
     NEMSHRIARD QLAFAETEME KARQRLDASK AELLSYQDNN NVLDPQAQAQ AASTLVNTLM
     GQKIQMEADL RNLLTYLRED APQVVSARNA IQSLQAQIDE EKSKITAPQG DKLNRMAVDF
     EEIKSKVEFN TELYKLTLTS IEKTRVEAAR KLKVLSVISS PQLPQESSFP NIPYLIACWL
     LVCCLLFGTL KLLLAVIEDH RD