ID   KPSM5_ECOLX             Reviewed;         258 AA.
AC   P24584;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Polysialic acid transport protein KpsM;
GN   Name=kpsM;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K5;
RX   PubMed=2082146; DOI=10.1111/j.1365-2958.1990.tb02035.x;
RA   Smith A.N., Boulnois G.J., Roberts I.S.;
RT   "Molecular analysis of the Escherichia coli K5 kps locus: identification
RT   and characterization of an inner-membrane capsular polysaccharide transport
RT   system.";
RL   Mol. Microbiol. 4:1863-1869(1990).
CC   -!- FUNCTION: KpsM and KpsT constitute a system for the transport of
CC       polysialic acid across the cytoplasmic membrane.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; X53819; CAA37815.1; -; Genomic_DNA.
DR   PIR; S12236; S12236.
DR   RefSeq; WP_000124291.1; NZ_WTRA01000005.1.
DR   AlphaFoldDB; P24584; -.
DR   SMR; P24584; -.
DR   TCDB; 3.A.1.101.1; the atp-binding cassette (abc) superfamily.
DR   OMA; AFRQVQP; -.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR013525; ABC_2_trans.
DR   InterPro; IPR000412; ABC_2_transport.
DR   Pfam; PF01061; ABC2_membrane; 1.
DR   PIRSF; PIRSF006648; DrrB; 1.
DR   PRINTS; PR00164; ABC2TRNSPORT.
DR   PROSITE; PS51012; ABC_TM2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..258
FT                   /note="Polysialic acid transport protein KpsM"
FT                   /id="PRO_0000182983"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          30..251
FT                   /note="ABC transmembrane type-2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
SQ   SEQUENCE   258 AA;  29562 MW;  7A94148CDBAC4CC8 CRC64;
     MARSGFEVQK VTVEALFLRE IRTRFGKFRL GYLWAILEPS AHLLILLGIF GYIMHRTMPD
     ISFPVFLLNG LIPFFIFSSI SNRSVGAIEA NQGLFNYRPV KPIDTIIARA LLETLIYVAV
     YILLMLIVWM AGEYFEITNF LQLVLTWSLL IILSCGIGLI FMVVGKTFPE MQKVLPILLK
     PLYFISCIMF PLHSIPKQYW SYLLWNPLVH VVELSREAVM PGYISEGVSL NYLAMFTLVT
     LFIGLALYRT REEAMLTS