ID   KPST1_ECOLX             Reviewed;         219 AA.
AC   P23888;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Polysialic acid transport ATP-binding protein KpsT;
GN   Name=kpsT;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K1;
RX   PubMed=1856162; DOI=10.1128/jb.173.15.4603-4610.1991;
RA   Pavelka M.S. Jr., Wright L.F., Silver R.P.;
RT   "Identification of two genes, kpsM and kpsT, in region 3 of the polysialic
RT   acid gene cluster of Escherichia coli K1.";
RL   J. Bacteriol. 173:4603-4610(1991).
RN   [2]
RP   CHARACTERIZATION.
RX   PubMed=8051103; DOI=10.1016/s0021-9258(17)32139-7;
RA   Pavelka M.S. Jr., Hayes S.F., Silver R.P.;
RT   "Characterization of KpsT, the ATP-binding component of the ABC-transporter
RT   involved with the export of capsular polysialic acid in Escherichia coli
RT   K1.";
RL   J. Biol. Chem. 269:20149-20158(1994).
CC   -!- FUNCTION: Putative ATP-binding protein, and an energy coupling
CC       component for the transport of polysialic acid across the cytoplasmic
CC       membrane.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; M57381; AAA24047.1; -; Genomic_DNA.
DR   PIR; B42469; B42469.
DR   RefSeq; WP_000590258.1; NZ_WVVR01000003.1.
DR   AlphaFoldDB; P23888; -.
DR   SMR; P23888; -.
DR   PRIDE; P23888; -.
DR   OMA; VHIVYRV; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03220; ABC_KpsT_Wzt; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015860; ABC_transpr_TagH-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Transport.
FT   CHAIN           1..219
FT                   /note="Polysialic acid transport ATP-binding protein KpsT"
FT                   /id="PRO_0000092394"
FT   DOMAIN          2..218
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         38..45
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   219 AA;  24939 MW;  F1C8B5EE2BF0B2DA CRC64;
     MIKIENLTKS YRTPTGRHYV FKNLNIIFPK GYNIALIGQN GAGKSTLLRI IGGIDRPDSG
     NIITEHKISW PVGLAGGFQG SLTGRENVKF VARLYAKRDE LNERVDFVEE FSELGKYFDM
     PIKTYSSGMR SRLAFGLSMA FKFDYYLIDE ITAVGDAKFK KKCSDIFDKI REKSHLIMVS
     HSERALKEYC DVAIYLNKEG QGKFYKNVTE AIADYKKDL