ID   KPTA1_ARCFU             Reviewed;         216 AA.
AC   O29841;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Probable RNA 2'-phosphotransferase 1;
DE            EC=2.7.1.-;
GN   Name=kptA1; OrderedLocusNames=AF_0406;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in
CC       which the phosphate is ADP-ribosylated by NAD followed by a presumed
CC       transesterification to release the RNA and generate ADP-ribose 1''-2''-
CC       cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KptA/TPT1 family. {ECO:0000305}.
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DR   EMBL; AE000782; AAB90829.1; -; Genomic_DNA.
DR   PIR; F69300; F69300.
DR   RefSeq; WP_010877913.1; NC_000917.1.
DR   AlphaFoldDB; O29841; -.
DR   SMR; O29841; -.
DR   STRING; 224325.AF_0406; -.
DR   DNASU; 1483622; -.
DR   EnsemblBacteria; AAB90829; AAB90829; AF_0406.
DR   GeneID; 24793945; -.
DR   KEGG; afu:AF_0406; -.
DR   eggNOG; arCOG04063; Archaea.
DR   HOGENOM; CLU_052998_4_1_2; -.
DR   OMA; EHGYFRG; -.
DR   OrthoDB; 74155at2157; -.
DR   PhylomeDB; O29841; -.
DR   BRENDA; 2.7.1.160; 414.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.970; -; 1.
DR   Gene3D; 3.20.170.30; -; 1.
DR   HAMAP; MF_00299; KptA; 1.
DR   InterPro; IPR002745; Ptrans_KptA/Tpt1.
DR   InterPro; IPR042081; RNA_2'-PTrans_C.
DR   InterPro; IPR022928; RNA_2'-PTrans_KptA.
DR   InterPro; IPR042080; RNA_2'-PTrans_N.
DR   PANTHER; PTHR12684; PTHR12684; 1.
DR   Pfam; PF01885; PTS_2-RNA; 1.
PE   3: Inferred from homology;
KW   NAD; Reference proteome; Transferase.
FT   CHAIN           1..216
FT                   /note="Probable RNA 2'-phosphotransferase 1"
FT                   /id="PRO_0000157485"
SQ   SEQUENCE   216 AA;  25065 MW;  B2FE92DECA698DA9 CRC64;
     MEEIRFCPEH GFYRGEKCRC GAEGELILPK EKVEKLGKFI SGVLRHFPDK FGLNMDENGW
     VNLESLARVV KRRYKWANIW LIKALVYSDE KQRYELKGDK IRARYGHSID VKLSDFPEAK
     EDVLYYGTSE EEAHRMLEIG IKPVNQRYVH LSTTIEKSKE VASIRTDTPI VLEIDAKKAR
     EDGIRIIKAN DLIALAEEIP AKYIKRQIVF NQYSSS