ID   KPTA2_ARCFU             Reviewed;         216 AA.
AC   O28719;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Probable RNA 2'-phosphotransferase 2;
DE            EC=2.7.1.-;
GN   Name=kptA2; OrderedLocusNames=AF_1553;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in
CC       which the phosphate is ADP-ribosylated by NAD followed by a presumed
CC       transesterification to release the RNA and generate ADP-ribose 1''-2''-
CC       cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KptA/TPT1 family. {ECO:0000305}.
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DR   EMBL; AE000782; AAB89693.1; -; Genomic_DNA.
DR   PIR; H69443; H69443.
DR   RefSeq; WP_010879050.1; NC_000917.1.
DR   AlphaFoldDB; O28719; -.
DR   SMR; O28719; -.
DR   STRING; 224325.AF_1553; -.
DR   PRIDE; O28719; -.
DR   EnsemblBacteria; AAB89693; AAB89693; AF_1553.
DR   GeneID; 1484781; -.
DR   KEGG; afu:AF_1553; -.
DR   eggNOG; arCOG04063; Archaea.
DR   HOGENOM; CLU_052998_4_1_2; -.
DR   OMA; TEEPVHC; -.
DR   OrthoDB; 74155at2157; -.
DR   PhylomeDB; O28719; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.970; -; 1.
DR   Gene3D; 3.20.170.30; -; 1.
DR   HAMAP; MF_00299; KptA; 1.
DR   InterPro; IPR002745; Ptrans_KptA/Tpt1.
DR   InterPro; IPR042081; RNA_2'-PTrans_C.
DR   InterPro; IPR022928; RNA_2'-PTrans_KptA.
DR   InterPro; IPR042080; RNA_2'-PTrans_N.
DR   PANTHER; PTHR12684; PTHR12684; 1.
DR   Pfam; PF01885; PTS_2-RNA; 1.
PE   3: Inferred from homology;
KW   NAD; Reference proteome; Transferase.
FT   CHAIN           1..216
FT                   /note="Probable RNA 2'-phosphotransferase 2"
FT                   /id="PRO_0000157486"
SQ   SEQUENCE   216 AA;  24525 MW;  893EFBFA39EB62BC CRC64;
     MDLGICKRCG EFEGSCECGK GEVLLKSEDR KKVSKFLSGL LRHFGRDFGV RLDEDGWAEL
     RDVLKILSER YGVGRKHVEL IVKFDPKGRF ELKNGRIRAK YGHSVEVRTD WSEGGEIPEK
     LYHATSPENL NSILKTGLLP MRRREVHMCS SPQEAIEVGK RHSSNPVLLE IDAKGLMQDG
     IEVRRKGKVY TVDFVPPKFI RVLSFDPRSP NPAKGY