ID   KPTA_PSEAE              Reviewed;         182 AA.
AC   Q9I778;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   11-JAN-2001, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Probable RNA 2'-phosphotransferase;
DE            EC=2.7.1.-;
GN   Name=kptA; OrderedLocusNames=PA0054;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in
CC       which the phosphate is ADP-ribosylated by NAD followed by a presumed
CC       transesterification to release the RNA and generate ADP-ribose 1''-2''-
CC       cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KptA/TPT1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE004091; AAG03444.1; -; Genomic_DNA.
DR   PIR; D83638; D83638.
DR   RefSeq; NP_248744.1; NC_002516.2.
DR   RefSeq; WP_003111523.1; NZ_QZGE01000015.1.
DR   AlphaFoldDB; Q9I778; -.
DR   SMR; Q9I778; -.
DR   STRING; 287.DR97_3011; -.
DR   PaxDb; Q9I778; -.
DR   PRIDE; Q9I778; -.
DR   EnsemblBacteria; AAG03444; AAG03444; PA0054.
DR   GeneID; 878088; -.
DR   KEGG; pae:PA0054; -.
DR   PATRIC; fig|208964.12.peg.57; -.
DR   PseudoCAP; PA0054; -.
DR   HOGENOM; CLU_052998_4_0_6; -.
DR   InParanoid; Q9I778; -.
DR   OMA; YLYHGTV; -.
DR   PhylomeDB; Q9I778; -.
DR   BioCyc; PAER208964:G1FZ6-56-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR   GO; GO:0000215; F:tRNA 2'-phosphotransferase activity; IBA:GO_Central.
DR   GO; GO:0008033; P:tRNA processing; IBA:GO_Central.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.970; -; 1.
DR   Gene3D; 3.20.170.30; -; 1.
DR   HAMAP; MF_00299; KptA; 1.
DR   InterPro; IPR002745; Ptrans_KptA/Tpt1.
DR   InterPro; IPR042081; RNA_2'-PTrans_C.
DR   InterPro; IPR022928; RNA_2'-PTrans_KptA.
DR   InterPro; IPR042080; RNA_2'-PTrans_N.
DR   PANTHER; PTHR12684; PTHR12684; 1.
DR   Pfam; PF01885; PTS_2-RNA; 1.
PE   3: Inferred from homology;
KW   NAD; Reference proteome; Transferase.
FT   CHAIN           1..182
FT                   /note="Probable RNA 2'-phosphotransferase"
FT                   /id="PRO_0000157481"
SQ   SEQUENCE   182 AA;  20024 MW;  2E3B121021AAF15E CRC64;
     MDRKTLDDTS KFLSYVLRHQ PEAIGLTLDG EGWADIDALI AGAARDGRAL DRMLLGAVVE
     NNDKKRFALS ADGQRIRAVQ GHSHAAVAIA YAPAVPPAVL YHGTASRFLD SIRERGLVPG
     SRHHVHLSAR RATALEVGRR YGSPVLLEID ARDMHLAGHL FHQAENGVWL TERVPVRFIR
     EA