ID   KPTA_STRGG              Reviewed;         189 AA.
AC   B1VP90;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Probable RNA 2'-phosphotransferase {ECO:0000255|HAMAP-Rule:MF_00299};
DE            EC=2.7.1.- {ECO:0000255|HAMAP-Rule:MF_00299};
GN   Name=kptA {ECO:0000255|HAMAP-Rule:MF_00299}; OrderedLocusNames=SGR_3640;
OS   Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=455632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / NBRC 13350;
RX   PubMed=18375553; DOI=10.1128/jb.00204-08;
RA   Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA   Yamashita A., Hattori M., Horinouchi S.;
RT   "Genome sequence of the streptomycin-producing microorganism Streptomyces
RT   griseus IFO 13350.";
RL   J. Bacteriol. 190:4050-4060(2008).
CC   -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in
CC       which the phosphate is ADP-ribosylated by NAD followed by a presumed
CC       transesterification to release the RNA and generate ADP-ribose 1''-2''-
CC       cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
CC       {ECO:0000255|HAMAP-Rule:MF_00299}.
CC   -!- SIMILARITY: Belongs to the KptA/TPT1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00299}.
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DR   EMBL; AP009493; BAG20469.1; -; Genomic_DNA.
DR   RefSeq; WP_012380051.1; NC_010572.1.
DR   AlphaFoldDB; B1VP90; -.
DR   SMR; B1VP90; -.
DR   STRING; 455632.SGR_3640; -.
DR   EnsemblBacteria; BAG20469; BAG20469; SGR_3640.
DR   GeneID; 6210074; -.
DR   KEGG; sgr:SGR_3640; -.
DR   PATRIC; fig|455632.4.peg.3708; -.
DR   eggNOG; COG1859; Bacteria.
DR   HOGENOM; CLU_052998_4_0_11; -.
DR   OMA; YLYHGTV; -.
DR   OrthoDB; 1893705at2; -.
DR   Proteomes; UP000001685; Chromosome.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.970; -; 1.
DR   Gene3D; 3.20.170.30; -; 1.
DR   HAMAP; MF_00299; KptA; 1.
DR   InterPro; IPR002745; Ptrans_KptA/Tpt1.
DR   InterPro; IPR042081; RNA_2'-PTrans_C.
DR   InterPro; IPR022928; RNA_2'-PTrans_KptA.
DR   InterPro; IPR042080; RNA_2'-PTrans_N.
DR   PANTHER; PTHR12684; PTHR12684; 1.
DR   Pfam; PF01885; PTS_2-RNA; 1.
PE   3: Inferred from homology;
KW   NAD; Transferase.
FT   CHAIN           1..189
FT                   /note="Probable RNA 2'-phosphotransferase"
FT                   /id="PRO_1000115316"
SQ   SEQUENCE   189 AA;  20932 MW;  E235AF681705987C CRC64;
     MDERRTVKVS KYLSKHLRHQ PERIGLTLDE NGWVAVEELL RAAARHGFAF SRAELDHVVA
     ANDKRRFTVE NGCAADGVHG DRIRANQGHT VAVDLDLPPA EPPAHLYHGT VARVMDAIRT
     EGLRPMARHH VHLSPDRETA TRVGARRGRP LVLTVDAGAM HRAGHVFRVS ANGVWLADAV
     PPRFLLLRG