ID   KPTA_THEKO              Reviewed;         180 AA.
AC   Q5JFX3;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable RNA 2'-phosphotransferase {ECO:0000255|HAMAP-Rule:MF_00299};
DE            EC=2.7.1.- {ECO:0000255|HAMAP-Rule:MF_00299};
GN   Name=kptA {ECO:0000255|HAMAP-Rule:MF_00299}; OrderedLocusNames=TK0302;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in
CC       which the phosphate is ADP-ribosylated by NAD followed by a presumed
CC       transesterification to release the RNA and generate ADP-ribose 1''-2''-
CC       cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
CC       {ECO:0000255|HAMAP-Rule:MF_00299}.
CC   -!- SIMILARITY: Belongs to the KptA/TPT1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00299}.
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DR   EMBL; AP006878; BAD84491.1; -; Genomic_DNA.
DR   RefSeq; WP_011249257.1; NC_006624.1.
DR   AlphaFoldDB; Q5JFX3; -.
DR   SMR; Q5JFX3; -.
DR   STRING; 69014.TK0302; -.
DR   EnsemblBacteria; BAD84491; BAD84491; TK0302.
DR   GeneID; 3234840; -.
DR   KEGG; tko:TK0302; -.
DR   PATRIC; fig|69014.16.peg.301; -.
DR   eggNOG; arCOG04063; Archaea.
DR   HOGENOM; CLU_052998_4_1_2; -.
DR   InParanoid; Q5JFX3; -.
DR   OMA; TEEPVHC; -.
DR   OrthoDB; 74155at2157; -.
DR   PhylomeDB; Q5JFX3; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR   GO; GO:0000215; F:tRNA 2'-phosphotransferase activity; IBA:GO_Central.
DR   GO; GO:0008033; P:tRNA processing; IBA:GO_Central.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IBA:GO_Central.
DR   Gene3D; 1.10.10.970; -; 1.
DR   Gene3D; 3.20.170.30; -; 1.
DR   HAMAP; MF_00299; KptA; 1.
DR   InterPro; IPR002745; Ptrans_KptA/Tpt1.
DR   InterPro; IPR042081; RNA_2'-PTrans_C.
DR   InterPro; IPR022928; RNA_2'-PTrans_KptA.
DR   InterPro; IPR042080; RNA_2'-PTrans_N.
DR   PANTHER; PTHR12684; PTHR12684; 1.
DR   Pfam; PF01885; PTS_2-RNA; 1.
PE   3: Inferred from homology;
KW   NAD; Reference proteome; Transferase.
FT   CHAIN           1..180
FT                   /note="Probable RNA 2'-phosphotransferase"
FT                   /id="PRO_0000157494"
SQ   SEQUENCE   180 AA;  20938 MW;  416897834F4F81AA CRC64;
     MKPERKRVSK LMAYILRHSP EEFGLRPDVE GFVSLNELVN ALKTVYPEVT EEFVREIVEN
     DPKGRYEIRG DRIRARYGHS FPVSLDHEED TESRFLYHGT PRRNLPSILK EGLKPMKRQY
     VHVSTDKIEA LETGRRHGRE VVLLVIDAEC LRKRGFKIYK AGKNVRIVER VPPDCITLAV