ID   KR111_CAPHI             Reviewed;         159 AA.
AC   Q6R648;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Keratin-associated protein 11-1;
DE   AltName: Full=High sulfur keratin-associated protein 11.1;
GN   Name=KRTAP11-1;
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Yin J., Li J.Q., Zhou H.M.;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: In the wool cortex, wool keratin intermediate filaments are
CC       embedded in an interfilamentous matrix, consisting of wool keratin-
CC       associated proteins (KRTAP), which are essential for the formation of a
CC       rigid and resistant wool shaft through their extensive disulfide bond
CC       cross-linking with abundant cysteine residues of wool keratins. The
CC       matrix proteins include the high-sulfur and high-glycine-tyrosine
CC       keratins.
CC   -!- TISSUE SPECIFICITY: Wool.
CC   -!- SIMILARITY: Belongs to the PMG family. {ECO:0000305}.
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DR   EMBL; AY510113; AAS00520.1; -; mRNA.
DR   RefSeq; NP_001272696.1; NM_001285767.1.
DR   AlphaFoldDB; Q6R648; -.
DR   STRING; 9925.ENSCHIP00000001409; -.
DR   PRIDE; Q6R648; -.
DR   Ensembl; ENSCHIT00000004008; ENSCHIP00000001409; ENSCHIG00000002902.
DR   GeneID; 100861173; -.
DR   KEGG; chx:100861173; -.
DR   CTD; 337880; -.
DR   GeneTree; ENSGT00730000111463; -.
DR   OMA; CQPVGGI; -.
DR   OrthoDB; 1477787at2759; -.
DR   Proteomes; UP000291000; Chromosome 1.
DR   Bgee; ENSCHIG00000002902; Expressed in skin of neck and 9 other tissues.
DR   GO; GO:0005829; C:cytosol; IEA:UniProt.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   InterPro; IPR007951; KRTAP_PMG.
DR   PANTHER; PTHR19051; PTHR19051; 1.
DR   Pfam; PF05287; PMG; 1.
PE   2: Evidence at transcript level;
KW   Keratin; Reference proteome; Repeat.
FT   CHAIN           1..159
FT                   /note="Keratin-associated protein 11-1"
FT                   /id="PRO_0000185195"
FT   REPEAT          107..116
FT                   /note="1"
FT   REPEAT          117..126
FT                   /note="2"
FT   REPEAT          127..136
FT                   /note="3"
FT   REPEAT          137..146
FT                   /note="4"
FT   REGION          107..146
FT                   /note="4 X 10 AA approximate repeats"
SQ   SEQUENCE   159 AA;  16843 MW;  56584612ABB8B705 CRC64;
     MSYSCSTRNC SSRRIGGEYA VPVVTVSSPE ADCLSGIYLP SSFQTGSWLL DHCQETCCEP
     TVCQSTCYQP TPCVSSPVQV TSRQTTCVSS PCSTTCSRPL TFISSGCQPL SGVSTVCKPV
     RSISTVCQPV GGVSTICQPT CGVSRTYQQS CVSSCRRIC