ID   KR134_MACFA             Reviewed;         156 AA.
AC   Q4W7G9;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Keratin-associated protein 13-4;
GN   Name=KRTAP13-4; Synonyms=KAP13.4;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Kim H., Park E.;
RT   "Comparative analysis of KAP13.3 and KAP13.4 genes in primates.";
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: In the hair cortex, hair keratin intermediate filaments are
CC       embedded in an interfilamentous matrix, consisting of hair keratin-
CC       associated proteins (KRTAP), which are essential for the formation of a
CC       rigid and resistant hair shaft through their extensive disulfide bond
CC       cross-linking with abundant cysteine residues of hair keratins. The
CC       matrix proteins include the high-sulfur and high-glycine-tyrosine
CC       keratins.
CC   -!- SUBUNIT: Interacts with hair keratins.
CC   -!- SIMILARITY: Belongs to the PMG family. {ECO:0000305}.
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DR   EMBL; AB195301; BAD98708.1; -; Genomic_DNA.
DR   RefSeq; XP_015302173.1; XM_015446687.1.
DR   AlphaFoldDB; Q4W7G9; -.
DR   STRING; 9541.XP_005548900.1; -.
DR   Ensembl; ENSMFAT00000079627; ENSMFAP00000060854; ENSMFAG00000061177.
DR   GeneID; 102124928; -.
DR   KEGG; mcf:102124928; -.
DR   eggNOG; ENOG502STG2; Eukaryota.
DR   GeneTree; ENSGT00940000162756; -.
DR   OrthoDB; 1292816at2759; -.
DR   Proteomes; UP000233100; Chromosome 3.
DR   GO; GO:0005829; C:cytosol; IEA:UniProt.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   InterPro; IPR007951; KRTAP_PMG.
DR   InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR   PANTHER; PTHR19051; PTHR19051; 1.
DR   Pfam; PF05287; PMG; 1.
PE   3: Inferred from homology;
KW   Keratin; Reference proteome; Repeat.
FT   CHAIN           1..156
FT                   /note="Keratin-associated protein 13-4"
FT                   /id="PRO_0000185207"
FT   REPEAT          37..46
FT                   /note="1"
FT   REPEAT          47..56
FT                   /note="2"
FT   REPEAT          57..66
FT                   /note="3"
FT   REPEAT          73..82
FT                   /note="4"
FT   REGION          37..82
FT                   /note="4 X 10 AA approximate repeats"
SQ   SEQUENCE   156 AA;  17278 MW;  4DDA0B8AD7AF9D20 CRC64;
     MSYNCCSGNF SSRSFGGYLH YPGCNPYSTA LCSPSICQLG SSLYRNCQKT CWEPTSCRKS
     CYRRRTSMLC SPCQTTCSRS LGFGSSSCHS QGYGSRSCYS LGSGSSGFRF LKYGGCGFPS
     LSYGSRFCYP NYLASRAWQS SCYRPICGSR FYQFTC