KR151_CAPHI
ID KR151_CAPHI Reviewed; 136 AA.
AC Q6R645;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 34.
DE RecName: Full=Keratin-associated protein 15-1;
DE AltName: Full=Keratin-associated protein 15.1;
GN Name=KRTAP15-1;
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Yin J., Li J.Q., Zhou H.M.;
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: In the hair cortex, hair keratin intermediate filaments are
CC embedded in an interfilamentous matrix, consisting of hair keratin-
CC associated proteins (KRTAP), which are essential for the formation of a
CC rigid and resistant hair shaft through their extensive disulfide bond
CC cross-linking with abundant cysteine residues of hair keratins. The
CC matrix proteins include the high-sulfur and high-glycine-tyrosine
CC keratins.
CC -!- SUBUNIT: Interacts with hair keratins. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PMG family. {ECO:0000305}.
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DR EMBL; AY510116; AAS00523.1; -; mRNA.
DR RefSeq; NP_001272700.1; NM_001285771.1.
DR AlphaFoldDB; Q6R645; -.
DR PRIDE; Q6R645; -.
DR Ensembl; ENSCHIT00010006194; ENSCHIP00010004446; ENSCHIG00010003211.
DR GeneID; 100861176; -.
DR KEGG; chx:100861176; -.
DR CTD; 254950; -.
DR OrthoDB; 1292816at2759; -.
DR Proteomes; UP000291000; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR InterPro; IPR007951; KRTAP_PMG.
DR PANTHER; PTHR19051; PTHR19051; 1.
DR Pfam; PF05287; PMG; 1.
PE 2: Evidence at transcript level;
KW Keratin; Reference proteome.
FT CHAIN 1..136
FT /note="Keratin-associated protein 15-1"
FT /id="PRO_0000223918"
SQ SEQUENCE 136 AA; 14608 MW; 866A8B6DF8FF52F3 CRC64;
MSFNCSTGNF SRSLGGYLGV PVSTCDSFYP SNVVYSPSTF QLGSTLYSDC QENFFRPVSF
QTPCAVTRSF QTSCSHPQNF IFRSPCQTIY TGSLGSGNIG LGSFGCGSTG FQSLGCGSNF
CSPTYVSSRS CRSSYY