ID   KR291_HUMAN             Reviewed;         341 AA.
AC   A8MX34;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Keratin-associated protein 29-1;
DE   AltName: Full=Keratin-associated protein 29.2;
GN   Name=KRTAP29-1; Synonyms=KAP29.2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the KRTAP type 10 family. {ECO:0000305}.
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DR   EMBL; AC006070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471152; EAW60724.1; -; Genomic_DNA.
DR   CCDS; CCDS62183.1; -.
DR   RefSeq; NP_001244238.1; NM_001257309.1.
DR   AlphaFoldDB; A8MX34; -.
DR   STRING; 9606.ENSP00000375148; -.
DR   BioMuta; KRTAP29-1; -.
DR   MassIVE; A8MX34; -.
DR   PaxDb; A8MX34; -.
DR   PeptideAtlas; A8MX34; -.
DR   PRIDE; A8MX34; -.
DR   DNASU; 100533177; -.
DR   Ensembl; ENST00000391353.1; ENSP00000375148.1; ENSG00000212658.1.
DR   Ensembl; ENST00000574737.1; ENSP00000461202.1; ENSG00000262542.1.
DR   Ensembl; ENST00000576125.1; ENSP00000459109.1; ENSG00000262218.1.
DR   GeneID; 100533177; -.
DR   KEGG; hsa:100533177; -.
DR   MANE-Select; ENST00000391353.1; ENSP00000375148.1; NM_001257309.1; NP_001244238.1.
DR   UCSC; uc031rai.1; human.
DR   CTD; 100533177; -.
DR   GeneCards; KRTAP29-1; -.
DR   HGNC; HGNC:34211; KRTAP29-1.
DR   HPA; ENSG00000212658; Tissue enriched (skin).
DR   neXtProt; NX_A8MX34; -.
DR   VEuPathDB; HostDB:ENSG00000212658; -.
DR   eggNOG; ENOG502RPU0; Eukaryota.
DR   GeneTree; ENSGT00940000164459; -.
DR   HOGENOM; CLU_062832_0_0_1; -.
DR   InParanoid; A8MX34; -.
DR   OMA; PCDTFPC; -.
DR   OrthoDB; 1161575at2759; -.
DR   PhylomeDB; A8MX34; -.
DR   PathwayCommons; A8MX34; -.
DR   Reactome; R-HSA-6805567; Keratinization.
DR   SignaLink; A8MX34; -.
DR   BioGRID-ORCS; 100533177; 13 hits in 1008 CRISPR screens.
DR   Pharos; A8MX34; Tdark.
DR   PRO; PR:A8MX34; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; A8MX34; protein.
DR   Bgee; ENSG00000212658; Expressed in granulocyte and 12 other tissues.
DR   GO; GO:0005829; C:cytosol; TAS:Reactome.
DR   GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR   InterPro; IPR002494; KAP.
DR   PANTHER; PTHR23262; PTHR23262; 1.
DR   Pfam; PF13885; Keratin_B2_2; 2.
PE   3: Inferred from homology;
KW   Keratin; Reference proteome; Repeat.
FT   CHAIN           1..341
FT                   /note="Keratin-associated protein 29-1"
FT                   /id="PRO_0000348961"
FT   REPEAT          5..9
FT                   /note="1"
FT   REPEAT          115..119
FT                   /note="2"
FT   REPEAT          120..124
FT                   /note="3"
FT   REPEAT          150..154
FT                   /note="4"
FT   REPEAT          240..244
FT                   /note="5"
FT   REPEAT          276..280
FT                   /note="6"
FT   REPEAT          307..311
FT                   /note="7"
FT   REGION          5..311
FT                   /note="7 X 5 AA repeats of C-C-X(3)"
SQ   SEQUENCE   341 AA;  35211 MW;  0242DF69ABC80278 CRC64;
     MADGCCPGNT TAIPAVPTIT TYPVKGGFRH ALCLPSSCHS RMWQLVTCQE SCQPSIGAPS
     GCDPASCQPT RLPATSCVGF VCQPMCSHAA CYQSGTGQSP CLVSSCQPSC SESTCCQEKC
     CDASPCQQSS CQESVCMSGS CQAACGQSVC CDAGSCQPSC SEVTSCPETS CLPTICTASP
     CQPTWCQGSS CQPVSGEGQP CKSTYYQPIC YIFKPCQSAL YMPVPCQPST CVFSSCNTTC
     CVPSHCQPPH CQLVPSTCFI YQPVANCQAP CSTKNCCKPA SCDTVISGQP TCDGPPSYNQ
     SGCKSACCVT GLGTSPSSGS NCLPTSCQPS CESSFCKATL C