ID   KRA3_CAPHI              Reviewed;         132 AA.
AC   P02442;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Keratin, high-sulfur matrix protein, IIIA3;
DE   AltName: Full=M2.6 protein;
OS   Capra hircus (Goat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Capra.
OX   NCBI_TaxID=9925;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=South African angora;
RA   Joubert F.J.;
RT   "Studies on the high-sulphur proteins of reduced mohair. The isolation and
RT   the amino acid sequence of protein SCMKB-M2.6.";
RL   J. S. Afr. Chem. Inst. 28:250-263(1975).
CC   -!- FUNCTION: The keratin products of mammalian epidermal derivatives such
CC       as wool and hair consist of microfibrils embedded in a rigid matrix of
CC       other proteins. The matrix proteins include the high-sulfur and high-
CC       tyrosine keratins, having molecular weights of 6-20 kDa, whereas the
CC       microfibrils contain the larger, low-sulfur keratins (40-56 kDa).
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DR   PIR; A92978; KRGT3J.
DR   PIR; B92978; KRGT3M.
DR   AlphaFoldDB; P02442; -.
DR   STRING; 9925.ENSCHIP00000004593; -.
DR   Proteomes; UP000291000; Unassembled WGS sequence.
DR   GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR   InterPro; IPR002494; KAP.
DR   PANTHER; PTHR23262; PTHR23262; 1.
DR   Pfam; PF01500; Keratin_B2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Keratin; Reference proteome.
FT   CHAIN           1..132
FT                   /note="Keratin, high-sulfur matrix protein, IIIA3"
FT                   /id="PRO_0000084321"
FT   VARIANT         23
FT                   /note="Y -> C (in minor component)"
FT   VARIANT         119
FT                   /note="Missing (in minor component)"
SQ   SEQUENCE   132 AA;  14255 MW;  6C0CC8BFA13AB28B CRC64;
     TGSCCGPTFS SLSCGGGCLQ PRYYRDPCCC RPVSCQTTVS RPVTFVSRCT RPICEPCRRP
     VCCDPCSLQE GCCRPITCCP TSCQAVVCRP CCWATTCCQP VSVQCPCCRP TSCQPAPCSR
     TTCRTFRTSP CC