ID   KRA3_SHEEP              Reviewed;         131 AA.
AC   P02441;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Keratin, high-sulfur matrix protein, IIIA3;
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=Merino;
RX   PubMed=4584026; DOI=10.1042/bj1330641;
RA   Swart L.S., Haylett T.;
RT   "Studies on the high-sulphur proteins of reduced merino wool. Amino acid
RT   sequence of protein SCMKB-3A3.";
RL   Biochem. J. 133:641-654(1973).
CC   -!- FUNCTION: The keratin products of mammalian epidermal derivatives such
CC       as wool and hair consist of microfibrils embedded in a rigid matrix of
CC       other proteins. The matrix proteins include the high-sulfur and high-
CC       tyrosine keratins, having molecular weights of 6-20 kDa, whereas the
CC       microfibrils contain the larger, low-sulfur keratins (40-56 kDa).
CC   -!- TISSUE SPECIFICITY: Wool.
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DR   PIR; A02840; KRSHA3.
DR   AlphaFoldDB; P02441; -.
DR   PRIDE; P02441; -.
DR   Proteomes; UP000002356; Unplaced.
DR   GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR   InterPro; IPR002494; KAP.
DR   PANTHER; PTHR23262; PTHR23262; 1.
DR   Pfam; PF01500; Keratin_B2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Keratin; Reference proteome.
FT   CHAIN           1..131
FT                   /note="Keratin, high-sulfur matrix protein, IIIA3"
FT                   /id="PRO_0000084322"
SQ   SEQUENCE   131 AA;  14164 MW;  8C0B56C0070B1C50 CRC64;
     TGSCCGPTFS SLSCGGGCLQ PRYYRDPCCC RPVSCQTVSR PVTFVPRCTR PICEPCRRPV
     CCDPCSLQEG CCRPITCCPT SCQAVVCRPC CWATTCCQPV SVQCPCCRPT SCQPAPCSRT
     TCRTFRTSPC C