ID   KRA92_PANTR             Reviewed;         170 AA.
AC   A5A6P5;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Keratin-associated protein 9-2;
DE   AltName: Full=Keratin-associated protein 9.2;
GN   Name=KRTAP9-2;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Skin;
RX   PubMed=17574350; DOI=10.1016/j.gene.2007.04.013;
RA   Sakate R., Suto Y., Imanishi T., Tanoue T., Hida M., Hayasaka I.,
RA   Kusuda J., Gojobori T., Hashimoto K., Hirai M.;
RT   "Mapping of chimpanzee full-length cDNAs onto the human genome unveils
RT   large potential divergence of the transcriptome.";
RL   Gene 399:1-10(2007).
CC   -!- FUNCTION: In the hair cortex, hair keratin intermediate filaments are
CC       embedded in an interfilamentous matrix, consisting of hair keratin-
CC       associated proteins (KRTAP), which are essential for the formation of a
CC       rigid and resistant hair shaft through their extensive disulfide bond
CC       cross-linking with abundant cysteine residues of hair keratins. The
CC       matrix proteins include the high-sulfur and high-glycine-tyrosine
CC       keratins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with hair keratins. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KRTAP type 9 family. {ECO:0000305}.
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DR   EMBL; AB222173; BAF62418.1; -; mRNA.
DR   RefSeq; NP_001182081.1; NM_001195152.1.
DR   AlphaFoldDB; A5A6P5; -.
DR   PaxDb; A5A6P5; -.
DR   Ensembl; ENSPTRT00000106231; ENSPTRP00000089277; ENSPTRG00000044531.
DR   GeneID; 742702; -.
DR   KEGG; ptr:742702; -.
DR   CTD; 83899; -.
DR   eggNOG; KOG4726; Eukaryota.
DR   GeneTree; ENSGT00940000156135; -.
DR   InParanoid; A5A6P5; -.
DR   OMA; CCSQTCC; -.
DR   Proteomes; UP000002277; Chromosome 17.
DR   GO; GO:0005829; C:cytosol; IEA:UniProt.
DR   GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR   InterPro; IPR002494; KAP.
DR   PANTHER; PTHR23262; PTHR23262; 1.
DR   Pfam; PF13885; Keratin_B2_2; 3.
PE   2: Evidence at transcript level;
KW   Keratin; Reference proteome; Repeat.
FT   CHAIN           1..170
FT                   /note="Keratin-associated protein 9-2"
FT                   /id="PRO_0000296677"
FT   REPEAT          8..12
FT                   /note="1"
FT   REPEAT          13..17
FT                   /note="2"
FT   REPEAT          18..22
FT                   /note="3"
FT   REPEAT          37..41
FT                   /note="4"
FT   REPEAT          42..46
FT                   /note="5"
FT   REPEAT          51..55
FT                   /note="6"
FT   REPEAT          61..65
FT                   /note="7"
FT   REPEAT          66..70
FT                   /note="8"
FT   REPEAT          75..79
FT                   /note="9"
FT   REPEAT          80..84
FT                   /note="10"
FT   REPEAT          85..89
FT                   /note="11"
FT   REPEAT          90..94
FT                   /note="12"
FT   REPEAT          95..99
FT                   /note="13"
FT   REPEAT          140..144
FT                   /note="14"
FT   REPEAT          145..149
FT                   /note="15"
FT   REPEAT          150..154
FT                   /note="16"
FT   REPEAT          164..168
FT                   /note="17"
FT   REGION          8..168
FT                   /note="17 X 5 AA repeats of C-C-[RQVSGE]-[SPTQ]-[TASP]"
SQ   SEQUENCE   170 AA;  17987 MW;  EA5A0EA5D307D939 CRC64;
     MTHCCSPCCQ PTCCRTTCCR TTCWKPTTVT TCSSTPCCQP TCCVSSCCQP CCCPTCCQNT
     CCRTTCCQPT CVTSCYQPSC CSTPCCQPTC CGSSCCGQTS CGQSSSCTPV YCRRTCYYPT
     NVCLPGCLNQ SCGSSCCQPC CHPACCETTC CRTTCFQPTC VSSCCQPSCC