ID   KRCL_CHICK              Reviewed;         128 AA.
AC   P25692;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Claw keratin;
DE            Short=C-ker;
DE            Short=cKer;
GN   Name=CKER1;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=White leghorn; TISSUE=Embryonic claw;
RX   PubMed=1711498; DOI=10.1016/0378-1119(91)90415-8;
RA   Whitbread L.A., Gregg K., Rogers G.E.;
RT   "The structure and expression of a gene encoding chick claw keratin.";
RL   Gene 101:223-229(1991).
CC   -!- TISSUE SPECIFICITY: Abundantly expressed in the claw and at a low level
CC       in feather tissue.
CC   -!- MISCELLANEOUS: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a
CC       complex mixture of very similar polypeptides.
CC   -!- SIMILARITY: Belongs to the avian keratin family. {ECO:0000305}.
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DR   EMBL; M37698; AAA62730.1; -; Genomic_DNA.
DR   PIR; JQ1002; JQ1002.
DR   AlphaFoldDB; P25692; -.
DR   PaxDb; P25692; -.
DR   VEuPathDB; HostDB:LOC430661; -.
DR   eggNOG; ENOG502TE1C; Eukaryota.
DR   InParanoid; P25692; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   InterPro; IPR003461; Keratin.
DR   PANTHER; PTHR31203; PTHR31203; 1.
DR   Pfam; PF02422; Keratin; 1.
PE   2: Evidence at transcript level;
KW   Keratin; Reference proteome; Repeat.
FT   INIT_MET        1
FT                   /note="Removed"
FT   CHAIN           2..128
FT                   /note="Claw keratin"
FT                   /id="PRO_0000097011"
FT   REPEAT          83..91
FT                   /note="1"
FT   REPEAT          92..100
FT                   /note="2"
FT   REPEAT          101..109
FT                   /note="3; approximate"
FT   REGION          83..104
FT                   /note="3 X 9 AA tandem repeats, Gly-rich"
SQ   SEQUENCE   128 AA;  12258 MW;  B12BC117D4BC47BA CRC64;
     MSCSSLCAPA CVATPTPLAD SCNEPCVRQC PDSTVVIQPP ATVVTFPGPI LSSFPQYAAV
     GSAGVPAVGS GMGGTFGRGA GFGGYGGLGG YGGYGGLGGY GGYGGFGSCG YGGFGRGYRS
     LLGSCGPC