ID   KRE1_CANAW              Reviewed;         130 AA.
AC   C4YLJ6; P28874; Q5A011;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Protein KRE1;
DE   Flags: Precursor;
GN   Name=KRE1; ORFNames=CAWG_01714;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=1938890; DOI=10.1128/jb.173.21.6859-6864.1991;
RA   Boone C., Sdicu A.-M., Laroche M., Bussey H.;
RT   "Isolation from Candida albicans of a functional homolog of the
RT   Saccharomyces cerevisiae KRE1 gene, which is involved in cell wall beta-
RT   glucan synthesis.";
RL   J. Bacteriol. 173:6859-6864(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in cell wall 1,6-beta-glucan assembly possibly by
CC       the addition of linear side chains of 1,6-linked Glc units to a highly
CC       branched 1,6- and 1,3-linked glucan backbone.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC       anchor {ECO:0000305}. Secreted, cell wall {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KRE1 family. {ECO:0000305}.
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DR   EMBL; M81588; AAA34348.1; -; Genomic_DNA.
DR   EMBL; CM000309; EEQ43477.1; -; Genomic_DNA.
DR   PIR; A41340; A41340.
DR   AlphaFoldDB; C4YLJ6; -.
DR   STRING; 5476.C4YLJ6; -.
DR   EnsemblFungi; EEQ43477; EEQ43477; CAWG_01714.
DR   VEuPathDB; FungiDB:CAWG_01714; -.
DR   HOGENOM; CLU_156717_1_0_1; -.
DR   OMA; LTICTAM; -.
DR   Proteomes; UP000001429; Chromosome R.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031505; P:fungal-type cell wall organization; IEA:InterPro.
DR   InterPro; IPR031452; Kre1.
DR   Pfam; PF17056; KRE1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cell wall; Cell wall biogenesis/degradation; Glycoprotein;
KW   GPI-anchor; Lipoprotein; Membrane; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..130
FT                   /note="Protein KRE1"
FT                   /id="PRO_0000413038"
FT   CARBOHYD        109
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   130 AA;  13856 MW;  C83C236DDFCD21C1 CRC64;
     MNVNSVIYYI LFLFASTILA ADKTSSSVSP TLVWVTGTDA NGKLATTQST YYQSFMSTYT
     TAETPSSGSI GLGSISGTVG EIRTYSMTTI SQGNGGLSKF NQNGLEMKNL SFVKLIGVSF
     IAFISFILLI