ID   KRE28_LACTC             Reviewed;         362 AA.
AC   C5DK07;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Spindle pole body component KRE28;
GN   Name=KRE28; OrderedLocusNames=KLTH0F00836g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Required for kinetochore binding by a discrete subset of
CC       kMAPs and motors. Involved in kinetochore-microtubule binding and the
CC       spindle assembly checkpoint (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, spindle pole body {ECO:0000250}. Nucleus membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Nucleoplasmic
CC       side {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}.
CC       Note=Localizes to the nuclear side of the spindle pole body.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KRE28 family. {ECO:0000305}.
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DR   EMBL; CU928170; CAR23808.1; -; Genomic_DNA.
DR   RefSeq; XP_002554245.1; XM_002554199.1.
DR   AlphaFoldDB; C5DK07; -.
DR   SMR; C5DK07; -.
DR   STRING; 559295.C5DK07; -.
DR   EnsemblFungi; CAR23808; CAR23808; KLTH0F00836g.
DR   GeneID; 8292436; -.
DR   KEGG; lth:KLTH0F00836g; -.
DR   eggNOG; ENOG502S19U; Eukaryota.
DR   HOGENOM; CLU_062083_0_0_1; -.
DR   InParanoid; C5DK07; -.
DR   OMA; LADECHT; -.
DR   OrthoDB; 1204570at2759; -.
DR   Proteomes; UP000002036; Chromosome F.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031361; Kre28.
DR   Pfam; PF17097; Kre28; 1.
PE   3: Inferred from homology;
KW   Centromere; Chromosome; Coiled coil; Cytoplasm; Cytoskeleton; Kinetochore;
KW   Membrane; Nucleus; Reference proteome.
FT   CHAIN           1..362
FT                   /note="Spindle pole body component KRE28"
FT                   /id="PRO_0000408563"
FT   COILED          6..62
FT                   /evidence="ECO:0000255"
FT   COILED          131..246
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   362 AA;  41242 MW;  383E44AA4346547D CRC64;
     MADDPTINGL ELQLNAAEEH ATALTEEALQ NQDLHYKEVV EQLKRSVEQL VEDNESLFTA
     VDLPPEVDPT CISGRILDLA QLTQQLKSTH LQQETLDNFL RYTISSTDIL QLESESDERY
     ASVSRAVSQL QDNDIIQLDS EVDQIKQDIR KAGQTIADQR EALNELCLET GNLADECHTL
     LSELEEATRT REMVEKQAAV EVTNDHPVEE MYASWQSLKE ELQQESHLRR HLNQLKQSKA
     SLEAILGTKN GNEHKDTNVM QEYASYDAFI RFWISKFTNK EMENLEVFPR SNKFQFTHRG
     TDVVISLGPR GISRVELYGK GIPLEKIAAA RKDVNEEASR GEELYMSINR IIDKIKEHTT
     VS