ID   KRE9_CANAX              Reviewed;         271 AA.
AC   O74226;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Cell wall synthesis protein KRE9;
DE   Flags: Precursor;
GN   Name=KRE9;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9707560; DOI=10.1073/pnas.95.17.9825;
RA   Lussier M., Sdicu A.-M., Shahinian S., Bussey H.;
RT   "The Candida albicans KRE9 gene is required for cell wall beta-1,6-glucan
RT   synthesis and is essential for growth on glucose.";
RL   Proc. Natl. Acad. Sci. U.S.A. 95:9825-9830(1998).
CC   -!- FUNCTION: Involved in cell wall beta(1->6) glucan synthesis.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000305}.
CC   -!- PTM: O-glycosylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KRE9/KNH1 family. {ECO:0000305}.
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DR   EMBL; AF069763; AAC32351.1; -; Genomic_DNA.
DR   AlphaFoldDB; O74226; -.
DR   VEuPathDB; FungiDB:C3_04180W_A; -.
DR   VEuPathDB; FungiDB:CAWG_02732; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0006078; P:(1->6)-beta-D-glucan biosynthetic process; IEA:InterPro.
DR   GO; GO:0042546; P:cell wall biogenesis; IEA:InterPro.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   InterPro; IPR045328; Kre9/Knh1.
DR   InterPro; IPR018466; Kre9/Knh1-like_N.
DR   InterPro; IPR008659; Kre9/Knh1_C.
DR   PANTHER; PTHR28154; PTHR28154; 1.
DR   Pfam; PF10342; GPI-anchored; 1.
DR   Pfam; PF05390; KRE9; 1.
PE   3: Inferred from homology;
KW   Cell wall; Cell wall biogenesis/degradation; Glycoprotein; Secreted;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..271
FT                   /note="Cell wall synthesis protein KRE9"
FT                   /id="PRO_0000016847"
SQ   SEQUENCE   271 AA;  29126 MW;  F4AF946B0FCC7448 CRC64;
     MRQFQIILIS LVVSIIRCVV ADVDITSPKS GETFSGSSGS ASIKITWDDS DDSDSPKSLD
     NAKGYTISLC TGPTSDGDIQ CLDPLVKNEA IAGKSKTVSI PQNSVPNGYY YFQIYVTFTN
     GGTTIHYSPR FKLTGMSGPT ATLDVTETGS VPADQASGFD TATTADSKSF TVPYTLQTGK
     TRYAPMQMQP GTKVTATTWS MKFPTSAVTY YSTKAGTPNV ASTITPGWSY TAESAVNYAS
     VAPYPTYWYP ASERVSKATI SAATKRRRWL D