ID   KRE9_CANGA              Reviewed;         276 AA.
AC   O74683;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Cell wall synthesis protein KRE9;
DE   Flags: Precursor;
GN   Name=KRE9; OrderedLocusNames=CAGL0C00363g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=9748432; DOI=10.1128/jb.180.19.5020-5029.1998;
RA   Nagahashi S., Lussier M., Bussey H.;
RT   "Isolation of Candida glabrata homologs of the Saccharomyces cerevisiae
RT   KRE9 and KNH1 genes and their involvement in cell wall beta-1,6-glucan
RT   synthesis.";
RL   J. Bacteriol. 180:5020-5029(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in cell wall beta(1->6) glucan synthesis.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000305}.
CC   -!- PTM: O-glycosylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KRE9/KNH1 family. {ECO:0000305}.
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DR   EMBL; AF064251; AAC64008.1; -; Genomic_DNA.
DR   EMBL; CR380949; CAG58101.1; -; Genomic_DNA.
DR   RefSeq; XP_445197.1; XM_445197.1.
DR   AlphaFoldDB; O74683; -.
DR   STRING; 5478.XP_445197.1; -.
DR   EnsemblFungi; CAG58101; CAG58101; CAGL0C00363g.
DR   GeneID; 2886951; -.
DR   KEGG; cgr:CAGL0C00363g; -.
DR   CGD; CAL0127358; KRE9.
DR   VEuPathDB; FungiDB:CAGL0C00363g; -.
DR   eggNOG; ENOG502S28F; Eukaryota.
DR   HOGENOM; CLU_063732_1_0_1; -.
DR   InParanoid; O74683; -.
DR   OMA; QMQPGST; -.
DR   Proteomes; UP000002428; Chromosome C.
DR   GO; GO:0005576; C:extracellular region; IDA:CGD.
DR   GO; GO:0062040; C:fungal biofilm matrix; IDA:CGD.
DR   GO; GO:0006078; P:(1->6)-beta-D-glucan biosynthetic process; IEA:InterPro.
DR   GO; GO:0006077; P:(1->6)-beta-D-glucan metabolic process; IMP:CGD.
DR   GO; GO:0042546; P:cell wall biogenesis; IEA:InterPro.
DR   GO; GO:0031505; P:fungal-type cell wall organization; IMP:CGD.
DR   InterPro; IPR045328; Kre9/Knh1.
DR   InterPro; IPR008659; Kre9/Knh1_C.
DR   PANTHER; PTHR28154; PTHR28154; 1.
DR   Pfam; PF05390; KRE9; 1.
PE   3: Inferred from homology;
KW   Cell wall; Cell wall biogenesis/degradation; Glycoprotein;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..276
FT                   /note="Cell wall synthesis protein KRE9"
FT                   /id="PRO_0000016848"
SQ   SEQUENCE   276 AA;  30549 MW;  5AA4328C8DC59EDD CRC64;
     MLLLAILLSL FALIRADVNI VEPGPGDTFS GADGTVSINL KWVDNGAYPP LDKVAYYLFS
     LCYGPNTKIQ CVYKPDTKIT PDDLDKDDAG TYSYKFDIQS SVVGSGQFYV QVFAWVDGQG
     YTLHYTPRIE LTNMGGPTTF ELLTYTDTIQ PVPQTSIRTG TDTNTQSFDA SSVYSLPYTE
     QTLKTRVAPI QQQPGTKVTA TTWSRRYPTS AVTFYSTFRS SLDQLSTLTP AWNYTVSSAV
     NYATPAAMPS DNGGWYNPIK RQSLSTRKLN VRYLSS