ID   KRFT_LARNO              Reviewed;          98 AA.
AC   P02451;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Feather keratin;
DE            Short=F-ker;
OS   Larus novaehollandiae (Silver gull) (Chroicocephalus novaehollandiae).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Charadriiformes; Laridae; Chroicocephalus.
OX   NCBI_TaxID=2547444;
RN   [1]
RP   PROTEIN SEQUENCE, AND ACETYLATION AT ALA-1.
RC   TISSUE=Feather calamus;
RX   PubMed=4429491; DOI=10.1071/bi9740369;
RA   O'Donnell I.J., Inglis A.S.;
RT   "Amino acid sequence of a feather keratin from silver gull (Larus novae-
RT   hollandiae) and comparison with one from emu (Dromaius novae-hollandiae).";
RL   Aust. J. Biol. Sci. 27:369-382(1974).
CC   -!- SUBUNIT: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a
CC       complex mixture of very similar polypeptides.
CC   -!- SIMILARITY: Belongs to the avian keratin family. {ECO:0000305}.
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DR   PIR; A02850; KRGLBS.
DR   AlphaFoldDB; P02451; -.
DR   iPTMnet; P02451; -.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   InterPro; IPR003461; Keratin.
DR   PANTHER; PTHR31203; PTHR31203; 1.
DR   Pfam; PF02422; Keratin; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Keratin.
FT   CHAIN           1..98
FT                   /note="Feather keratin"
FT                   /id="PRO_0000097007"
FT   MOD_RES         1
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000269|PubMed:4429491"
FT   VARIANT         39
FT                   /note="V -> Q"
FT   VARIANT         48
FT                   /note="S -> T"
FT   VARIANT         55
FT                   /note="A -> V"
FT   VARIANT         56
FT                   /note="V -> A"
FT   VARIANT         62
FT                   /note="S -> A"
FT   VARIANT         63
FT                   /note="S -> A"
FT   VARIANT         76
FT                   /note="Y -> I"
FT   VARIANT         78
FT                   /note="G -> S"
FT   VARIANT         80
FT                   /note="G -> Y"
FT   VARIANT         89
FT                   /note="F -> Y"
FT   UNSURE          4
FT                   /note="D or N"
FT   UNSURE          27
FT                   /note="E or Q"
FT   UNSURE          75..83
SQ   SEQUENCE   98 AA;  9741 MW;  D7727A5776194C2F CRC64;
     ACNDLCGPCG PTPLANSCNE PCVRQCEASR VVIQPSTVVV TLPGPILSSF PQSTAVGGSA
     SSSVGNELLA SQGVPYFGGG FGLGGLGCFS GRRGCYPC