KRI1_SCHPO
ID KRI1_SCHPO Reviewed; 598 AA.
AC Q09799;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Protein kri1;
GN Name=kri1; ORFNames=SPAC22G7.05;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-222; SER-225 AND SER-476, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: Required for 40S ribosome biogenesis. Involved in nucleolar
CC processing of pre-18S ribosomal RNA (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KRI1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAA91129.1; -; Genomic_DNA.
DR PIR; T11615; T11615.
DR RefSeq; NP_593054.1; NM_001018452.2.
DR AlphaFoldDB; Q09799; -.
DR SMR; Q09799; -.
DR BioGRID; 278150; 9.
DR STRING; 4896.SPAC22G7.05.1; -.
DR iPTMnet; Q09799; -.
DR MaxQB; Q09799; -.
DR PaxDb; Q09799; -.
DR PRIDE; Q09799; -.
DR EnsemblFungi; SPAC22G7.05.1; SPAC22G7.05.1:pep; SPAC22G7.05.
DR GeneID; 2541654; -.
DR KEGG; spo:SPAC22G7.05; -.
DR PomBase; SPAC22G7.05; kri1.
DR VEuPathDB; FungiDB:SPAC22G7.05; -.
DR eggNOG; KOG2409; Eukaryota.
DR HOGENOM; CLU_009647_2_0_1; -.
DR InParanoid; Q09799; -.
DR OMA; QWRKETF; -.
DR PhylomeDB; Q09799; -.
DR PRO; PR:Q09799; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; ISO:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR InterPro; IPR018034; Kri1.
DR InterPro; IPR024626; Kri1-like_C.
DR PANTHER; PTHR14490; PTHR14490; 1.
DR Pfam; PF05178; Kri1; 1.
DR Pfam; PF12936; Kri1_C; 1.
PE 1: Evidence at protein level;
KW Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..598
FT /note="Protein kri1"
FT /id="PRO_0000116407"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 83..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..114
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 222
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 225
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 476
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 598 AA; 69524 MW; 5C6A68D67AC0FBB5 CRC64;
MPRKKSAAKK AREALVQKKV INSNVPTDKK SIDQLQENVT SKSHLLEESS SEDEEINSFQ
INEEYAKRFE HNKKREELQK LEAKYGEQMA NGVDGEGSDE SSSEEEEDSD GELVTPEVDA
AILRMIVKIR NKDPDLYDSQ QKYFDEVEKD VQGSLKSKDG FRSVTLKDYH RQKLLSGEIL
DAEEDEPMPN DANPTHVEEQ ERLRKETIAA FHDVNGNKDA VSNESDEDGD FLVKKEKTKK
QLEEEEHGYE RFLLESAQSK EARKVLEDLS SSYVKQRPSV LVNTEDDENG IKPSDEDFLL
KYMMNRGWRT SNTKQPSYEE IIDEVDAENR FDEDAEEFEN KFNFRFEEEA GSQIVSHPRN
VADSLRRKDD SRKRARDRKK ERLEEASQKR LEEVNRLKNL KRKELEEKLN QVIEIAGSKN
IDVSKLDLDE DFDPEKWESK MSEIFNENYY EEDSAKKPEF GDDIDIDDIA QVDNGSEDLG
SIENKTVEDT GNREKSKKSL RKDIREKKRK IDEYVEEKYG VPEAVIVKNS KFRYQQVAPE
TFGLDILDIL NASDADLNNY VGLKKMTPYR TPEEIARDKK KYGKKKRLRE WKKQVFGK
