KRP4_ORYSJ
ID KRP4_ORYSJ Reviewed; 194 AA.
AC Q7XDH8; A3C5N3; B7EMP9; Q283L1; Q9FW65;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Cyclin-dependent kinase inhibitor 4;
DE AltName: Full=KIP-related protein 4;
GN Name=KRP4; OrderedLocusNames=Os10g0471700, LOC_Os10g33310;
GN ORFNames=OsJ_030605, OSJNBb0094K03.16;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RX PubMed=17012406; DOI=10.1104/pp.106.087056;
RA Barroco R.M., Peres A., Droual A.-M., de Veylder L., Nguyen L.S.L.,
RA de Wolf J., Mironov V., Peerbolte R., Beemster G.T.S., Inze D.,
RA Broekaert W.F., Frankard V.;
RT "The cyclin-dependent kinase inhibitor Orysa;KRP1 plays an important role
RT in seed development of rice.";
RL Plant Physiol. 142:1053-1064(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP INDUCTION, AND GENE FAMILY.
RX PubMed=17443292; DOI=10.1007/s11103-007-9154-y;
RA Guo J., Song J., Wang F., Zhang X.S.;
RT "Genome-wide identification and expression analysis of rice cell cycle
RT genes.";
RL Plant Mol. Biol. 64:349-360(2007).
CC -!- DEVELOPMENTAL STAGE: Expressed at the time of pollination and then
CC immediately decreases to basal level. {ECO:0000269|PubMed:17012406}.
CC -!- INDUCTION: Down-regulated by cytokinin. {ECO:0000269|PubMed:17443292}.
CC -!- SIMILARITY: Belongs to the CDI family. ICK/KRP subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG16867.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DQ229365; ABB70061.1; -; mRNA.
DR EMBL; AC069145; AAG16867.1; ALT_SEQ; Genomic_DNA.
DR EMBL; DP000086; AAP54233.2; -; Genomic_DNA.
DR EMBL; AP008216; BAF26743.1; -; Genomic_DNA.
DR EMBL; AP014966; BAT11263.1; -; Genomic_DNA.
DR EMBL; CM000147; EAZ16396.1; -; Genomic_DNA.
DR EMBL; AK073804; BAG93646.1; -; mRNA.
DR RefSeq; XP_015612960.1; XM_015757474.1.
DR AlphaFoldDB; Q7XDH8; -.
DR STRING; 4530.OS10T0471700-02; -.
DR PaxDb; Q7XDH8; -.
DR PRIDE; Q7XDH8; -.
DR EnsemblPlants; Os10t0471700-02; Os10t0471700-02; Os10g0471700.
DR GeneID; 4348872; -.
DR Gramene; Os10t0471700-02; Os10t0471700-02; Os10g0471700.
DR KEGG; osa:4348872; -.
DR eggNOG; ENOG502QXA1; Eukaryota.
DR HOGENOM; CLU_083146_0_1_1; -.
DR InParanoid; Q7XDH8; -.
DR OMA; HTPTSHE; -.
DR OrthoDB; 1397852at2759; -.
DR PlantReactome; R-OSA-9640760; G1 phase.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000007752; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR ExpressionAtlas; Q7XDH8; baseline and differential.
DR Genevisible; Q7XDH8; OS.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IEA:InterPro.
DR Gene3D; 4.10.365.10; -; 1.
DR InterPro; IPR003175; CDI_dom.
DR InterPro; IPR044898; CDI_dom_sf.
DR InterPro; IPR044275; KRP.
DR PANTHER; PTHR46776; PTHR46776; 1.
DR Pfam; PF02234; CDI; 1.
DR PIRSF; PIRSF017811; CDK_inhib_pln; 1.
PE 2: Evidence at transcript level;
KW Protein kinase inhibitor; Reference proteome.
FT CHAIN 1..194
FT /note="Cyclin-dependent kinase inhibitor 4"
FT /id="PRO_0000295667"
FT REGION 49..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 107..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 57
FT /note="E -> K (in Ref. 6; EAZ16396)"
FT /evidence="ECO:0000305"
FT CONFLICT 85..86
FT /note="SA -> NP (in Ref. 6; EAZ16396)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 194 AA; 21308 MW; C80BCD00EEF339E2 CRC64;
MGKYMRKAKV VVSGEVVAAA VMELAAAPLG VRTRARSLAL QKRQGGEYLE LRSRRLEKLP
PPPPPPPRRR ATAAAATADA TAAESAEAEV SFGGENVLEL EAMERNTRET TPCSLIRDPD
TISTPGSTTR RSHSSSHCKV QTPVRHNIIP ASAELEAFFA AEEQRQRQAF IDKYNFDPVN
DCPLPGRFEW VKLD
