ARC5B_ARATH
ID ARC5B_ARATH Reviewed; 135 AA.
AC B3H6Y2;
DT 29-MAY-2013, integrated into UniProtKB/Swiss-Prot.
DT 22-JUL-2008, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Actin-related protein 2/3 complex subunit 5B;
DE AltName: Full=Actin-related protein C5B;
DE AltName: Full=Arp2/3 complex 16 kDa subunit;
DE Short=p16-ARC;
GN Name=ARPC5B; OrderedLocusNames=At5g65274; ORFNames=MQN23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15653407; DOI=10.1016/j.pbi.2004.11.004;
RA Szymanski D.B.;
RT "Breaking the WAVE complex: the point of Arabidopsis trichomes.";
RL Curr. Opin. Plant Biol. 8:103-112(2005).
CC -!- FUNCTION: Functions as component of the Arp2/3 complex which is
CC involved in regulation of actin polymerization and together with an
CC activating nucleation-promoting factor (NPF) mediates the formation of
CC branched actin networks. Arp2/3 complex plays a critical role in the
CC control of cell morphogenesis via the modulation of cell polarity
CC development. {ECO:0000250}.
CC -!- SUBUNIT: Component of the Arp2/3 complex composed of ARP2, ARP3,
CC ARPC1/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and
CC ARPC5/p16-ARC. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell
CC projection {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ARPC5 family. {ECO:0000305}.
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DR EMBL; AB013395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED98032.1; -; Genomic_DNA.
DR RefSeq; NP_001119503.1; NM_001126031.1.
DR AlphaFoldDB; B3H6Y2; -.
DR SMR; B3H6Y2; -.
DR STRING; 3702.AT5G65274.1; -.
DR PaxDb; B3H6Y2; -.
DR PRIDE; B3H6Y2; -.
DR EnsemblPlants; AT5G65274.1; AT5G65274.1; AT5G65274.
DR GeneID; 6240785; -.
DR Gramene; AT5G65274.1; AT5G65274.1; AT5G65274.
DR KEGG; ath:AT5G65274; -.
DR Araport; AT5G65274; -.
DR TAIR; locus:4515103762; AT5G65274.
DR eggNOG; KOG3380; Eukaryota.
DR HOGENOM; CLU_101888_3_0_1; -.
DR InParanoid; B3H6Y2; -.
DR OMA; KHYKHVE; -.
DR OrthoDB; 1565115at2759; -.
DR PhylomeDB; B3H6Y2; -.
DR PRO; PR:B3H6Y2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; B3H6Y2; baseline.
DR GO; GO:0005885; C:Arp2/3 protein complex; IBA:GO_Central.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IBA:GO_Central.
DR GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR Gene3D; 1.25.40.190; -; 1.
DR InterPro; IPR006789; ARPC5.
DR InterPro; IPR036743; ARPC5_sf.
DR PANTHER; PTHR12644; PTHR12644; 1.
DR Pfam; PF04699; P16-Arc; 1.
DR SUPFAM; SSF69103; SSF69103; 1.
PE 3: Inferred from homology;
KW Actin-binding; Cell projection; Cytoplasm; Cytoskeleton;
KW Reference proteome.
FT CHAIN 1..135
FT /note="Actin-related protein 2/3 complex subunit 5B"
FT /id="PRO_0000422533"
SQ SEQUENCE 135 AA; 15065 MW; 912DD4CABD2241F5 CRC64;
MAGAAAFVEA DNAEEIMARI ETKSQKIESL LKHYKHVEAL KTALDGSPPK TLDERCKSAN
WIVVHRAIMA IKDIEGMLNS LTAEYYDILM KYLYRGLSTG DEPTCEQCLM IHEKLTERAG
LGCILRCLSD TTNTV