KRUP_PSYCI
ID KRUP_PSYCI Reviewed; 74 AA.
AC Q02035;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Protein krueppel;
DE Flags: Fragment;
GN Name=Kr;
OS Psychoda cinerea (Psychod fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Psychoda.
OX NCBI_TaxID=7202;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1438276; DOI=10.1073/pnas.89.22.10782;
RA Sommer R.J., Retzlaff M., Goerlich K., Sander K., Tautz D.;
RT "Evolutionary conservation pattern of zinc-finger domains of Drosophila
RT segmentation genes.";
RL Proc. Natl. Acad. Sci. U.S.A. 89:10782-10786(1992).
CC -!- FUNCTION: Krueppel is a gap class segmentation protein.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000305}.
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DR EMBL; L01609; AAA29799.1; -; Genomic_DNA.
DR AlphaFoldDB; Q02035; -.
DR SMR; Q02035; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0035282; P:segmentation; IEA:UniProtKB-KW.
DR InterPro; IPR031243; Krueppel.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24390:SF151; PTHR24390:SF151; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 3: Inferred from homology;
KW Developmental protein; DNA-binding; Gap protein; Metal-binding; Nucleus;
KW Repeat; Zinc; Zinc-finger.
FT CHAIN <1..>74
FT /note="Protein krueppel"
FT /id="PRO_0000047000"
FT ZN_FING <1..4
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 10..32
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 38..60
FT /note="C2H2-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 66..>74
FT /note="C2H2-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT NON_TER 1
FT NON_TER 74
SQ SEQUENCE 74 AA; 8931 MW; 34543F71D15E9E9D CRC64;
ERTHTGEKPF ECPECHKRFT RDHHLKTHMR LHTGEKPYHC SHCDRQFVQV ANLRRHLRVH
TGERPYACEL CDAR