ID   KS1_HYDVU               Reviewed;         217 AA.
AC   P38978;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=KS1 protein;
DE   AltName: Full=Head-specific protein 1;
DE   AltName: Full=Kopf-spezifisches protein 1;
DE   Flags: Precursor;
GN   Name=KS1;
OS   Hydra vulgaris (Hydra) (Hydra attenuata).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Aplanulata; Hydridae; Hydra.
OX   NCBI_TaxID=6087;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=7956827; DOI=10.1242/dev.120.9.2511;
RA   Weinziger R., Salgado L.M., David C.N., Bosch T.C.G.;
RT   "Ks1, an epithelial cell-specific gene, responds to early signals of head
RT   formation in Hydra.";
RL   Development 120:2511-2517(1994).
CC   -!- FUNCTION: Responds to early signals of head formation in hydra.
CC   -!- TISSUE SPECIFICITY: Expressed in tentacle-specific epithelial cells
CC       (battery cells) as well as in a small fraction of ectodermal epithelial
CC       cells in the gastric region subjacent to the tentacles (the tentacle
CC       formation region). The later cells are committed to become battery
CC       cells.
CC   -!- INDUCTION: By PKC.
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DR   EMBL; X78596; CAA55331.1; -; mRNA.
DR   PIR; S43193; S43193.
DR   AlphaFoldDB; P38978; -.
DR   Proteomes; UP000694840; Unplaced.
PE   2: Evidence at transcript level;
KW   Developmental protein; Reference proteome; Repeat; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..217
FT                   /note="KS1 protein"
FT                   /id="PRO_0000021570"
FT   REPEAT          32..81
FT                   /note="1"
FT   REPEAT          98..147
FT                   /note="2"
FT   REGION          24..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          32..147
FT                   /note="2 X 50 AA approximate repeats"
FT   REGION          72..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..50
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..92
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..114
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        115..143
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..185
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..205
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   217 AA;  25427 MW;  0010423D1364B4B8 CRC64;
     MKLIIVLVMM LVCVYSMSIE KNIPKNHEVP AKKQFAETKV EKKKRSDDGD EEICDDDDED
     CEDVVDIEEC NEDDDDCVDG GETEECDEDD DDCQEEKKKK KRETKPKLKK RNDDEEEEEC
     EEDDEDCEVE VDIEECDEED DDCYDEDKKK KKENKLKKES KKKNSKKTVP KNAKKSSKRS
     TSTKKTSQKK QQDKRGAIQK NLKIKEANFK KKFNLNF