ID   KTI12_DANRE             Reviewed;         275 AA.
AC   Q0P457; Q1MT61;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 2.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Protein KTI12 homolog;
GN   Name=kti12; ORFNames=si:dkey-77f17.5, zgc:153393;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the KTI12 family. {ECO:0000305}.
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DR   EMBL; AL935332; CAK11175.2; -; Genomic_DNA.
DR   EMBL; BC122265; AAI22266.1; -; mRNA.
DR   RefSeq; NP_001119890.1; NM_001126418.1.
DR   AlphaFoldDB; Q0P457; -.
DR   SMR; Q0P457; -.
DR   STRING; 7955.ENSDARP00000113245; -.
DR   PaxDb; Q0P457; -.
DR   Ensembl; ENSDART00000076484; ENSDARP00000070956; ENSDARG00000054301.
DR   Ensembl; ENSDART00000136776; ENSDARP00000113245; ENSDARG00000054301.
DR   GeneID; 751662; -.
DR   KEGG; dre:751662; -.
DR   CTD; 112970; -.
DR   ZFIN; ZDB-GENE-060825-174; kti12.
DR   eggNOG; KOG3062; Eukaryota.
DR   GeneTree; ENSGT00390000002443; -.
DR   HOGENOM; CLU_027147_1_0_1; -.
DR   InParanoid; Q0P457; -.
DR   OMA; FCIARER; -.
DR   OrthoDB; 1300128at2759; -.
DR   PhylomeDB; Q0P457; -.
DR   TreeFam; TF312974; -.
DR   PRO; PR:Q0P457; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 18.
DR   Bgee; ENSDARG00000054301; Expressed in early embryo and 22 other tissues.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR045106; Kti12.
DR   InterPro; IPR013641; KTI12/PSTK.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12435; PTHR12435; 1.
DR   Pfam; PF08433; KTI12; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..275
FT                   /note="Protein KTI12 homolog"
FT                   /id="PRO_0000285689"
FT   BINDING         8..15
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        212
FT                   /note="K -> R (in Ref. 2; AAI22266)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   275 AA;  31606 MW;  F0CA52DF23C961A0 CRC64;
     MPLILMCGYP CSGKTRRAQE LRDYFTQNTG RKVHIVGDED QGIDKNSVYA DSQKEKNLRG
     ALRAEVERKV NKDDIVILDS LNYIKGYRYE LFCLIKHTQT PHCLVYSLTS ADLSSEWNKD
     READSQYTQE ILDALILRFE APDSRNRWDS PLFTIQQDDS LPFEAICDAL FKRKAPPPNQ
     STKSQPLSST NFLYELDKVT QDVLMAVLES QKTSVPGDLI SIPGATEKIE LTRSLNMVEL
     RKLRRQFISY TKMHPTENIG QIANMFVQYL NKSMH