KTI1_XANSA
ID KTI1_XANSA Reviewed; 19 AA.
AC P86930;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 1.
DT 25-MAY-2022, entry version 10.
DE RecName: Full=Kunitz-type serine protease inhibitor 1 {ECO:0000303|PubMed:21520894};
DE Short=Xb-KTI {ECO:0000303|PubMed:21520894};
DE Flags: Fragment;
OS Xanthosoma sagittifolium (Elephant's ear) (Arum sagittifolium).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Araceae; Aroideae; Caladieae;
OC Xanthosoma.
OX NCBI_TaxID=28478;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, AND FUNCTION.
RC TISSUE=Corm {ECO:0000269|PubMed:21520894};
RX PubMed=21520894; DOI=10.1021/np200312r;
RA Lima T.B., Silva O.N., Migliolo L., Souza-Filho C.R., Goncalves E.G.,
RA Vasconcelos I.M., Oliveira J.T., Amaral A.C., Franco O.L.;
RT "A Kunitz proteinase inhibitor from corms of Xanthosoma blandum with
RT bactericidal activity.";
RL J. Nat. Prod. 74:969-975(2011).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION.
RA Franco O.L.;
RL Submitted (JUN-2011) to UniProtKB.
CC -!- FUNCTION: Serine protease inhibitor. Displays antimicrobial activity
CC against the Gram-negative bacterium S.typhimurium ATCC 14028. Displays
CC no hemolytic activity. {ECO:0000269|PubMed:21520894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|Ref.2}.
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DR AlphaFoldDB; P86930; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Antibiotic; Antimicrobial; Cytoplasm; Direct protein sequencing;
KW Protease inhibitor; Serine protease inhibitor.
FT PEPTIDE 1..>19
FT /note="Kunitz-type serine protease inhibitor 1"
FT /evidence="ECO:0000269|PubMed:21520894"
FT /id="PRO_0000413067"
FT NON_TER 19
FT /evidence="ECO:0000303|PubMed:21520894"
SQ SEQUENCE 19 AA; 2194 MW; C7FDFCBABADD8296 CRC64;
PVVDTTGNNP LQQQEEYYV