ID   KUP1_BIFLO              Reviewed;         597 AA.
AC   Q8G6U3;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Probable potassium transport system protein kup 1;
GN   Name=kup1; OrderedLocusNames=BL0545;
OS   Bifidobacterium longum (strain NCC 2705).
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=206672;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCC 2705;
RX   PubMed=12381787; DOI=10.1073/pnas.212527599;
RA   Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B., Pessi G.,
RA   Zwahlen M.-C., Desiere F., Bork P., Delley M., Pridmore R.D., Arigoni F.;
RT   "The genome sequence of Bifidobacterium longum reflects its adaptation to
RT   the human gastrointestinal tract.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000305}.
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DR   EMBL; AE014295; AAN24369.1; -; Genomic_DNA.
DR   RefSeq; NP_695733.1; NC_004307.2.
DR   AlphaFoldDB; Q8G6U3; -.
DR   EnsemblBacteria; AAN24369; AAN24369; BL0545.
DR   KEGG; blo:BL0545; -.
DR   PATRIC; fig|206672.9.peg.1287; -.
DR   HOGENOM; CLU_008142_4_1_11; -.
DR   OMA; AILMIMY; -.
DR   PhylomeDB; Q8G6U3; -.
DR   Proteomes; UP000000439; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003855; K+_transporter.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Potassium; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..597
FT                   /note="Probable potassium transport system protein kup 1"
FT                   /id="PRO_0000208993"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        329..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   597 AA;  66382 MW;  7CBE83EEF8BA477E CRC64;
     MGCLDVRFCR IIFALYSLIR KYGAWLVIPA MLGGAAFLAD SVLTPAVSIS SAVEGLKTLP
     ALEHLFTENK DLTMMITAVI IVILFAVQSR GTESIGKVFG SVVMVWFAFL AIVGVVAIGN
     DWSVLAALNP YYGIKFLFSP NNATGLALMG TVFLSTTGAE ALYSDMGHVG RGNIYFTWPF
     IKVALVLNYF GQGAWMLHNQ NNPELADAEG INPFFQMMDP NVRYVAVVLS VTAGIIASQA
     LITGAFTMVS EATGLNWMPH LQVCYPARTR GQLYIPVVNV VLCVATLAVL LLFRDSEHIS
     AAYGLALTIT MITTTILLGI YLWHRSNKFG AVVFTIVFLA IQVLFFAASM AKFLHGGWFT
     LLLTLAILMI MYTWNEGTKL ERSQRRHMMP KDFLPALDKL HGDSRIHRFA DNIVYLTSDP
     DLKRLDTDIF FSIFADHPKR ARAWWAVAVE TTDEPFTREY SVESFGTDYL FRVRIRLGFK
     VSQSIPAYLH QIMHDLEKTG ELPNQQSIYP KLDADPGIGT IRYVVIHKAL MPESKVSGRG
     ALSLQIKYAI RRVAGSPVKW FGLAPYNPLV EVQPLFVSTR RPPRLTRVAS QAPKREG