ID   KUP1_GEOSL              Reviewed;         631 AA.
AC   Q74AK4;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Probable potassium transport system protein kup 1 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup1 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=GSU2350;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; AE017180; AAR35724.1; -; Genomic_DNA.
DR   RefSeq; NP_953397.1; NC_002939.5.
DR   RefSeq; WP_010942985.1; NC_002939.5.
DR   AlphaFoldDB; Q74AK4; -.
DR   STRING; 243231.GSU2350; -.
DR   EnsemblBacteria; AAR35724; AAR35724; GSU2350.
DR   KEGG; gsu:GSU2350; -.
DR   PATRIC; fig|243231.5.peg.2380; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_7; -.
DR   InParanoid; Q74AK4; -.
DR   OMA; AADQFEI; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..631
FT                   /note="Probable potassium transport system protein kup 1"
FT                   /id="PRO_0000209016"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        402..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   631 AA;  68731 MW;  E23610C9B7B8FF83 CRC64;
     MEKNGTVHTG TVRQSLGLSL AALGVVYGDI GTSPLYAMRE CFHGTHPHPA TPDNVLGVLS
     LIVWALILIV SLKYLVFVLR ADNRGEGGIL ALTALLNPWG DENRPPRKVL VFLGLFGAAL
     LYGDGTLTPA ISVLSAIEGL KIATPLFHPY IVPITVVILI LLFLIQHRGT ARVGALFGPV
     MVLWFTVLAL LGIRGIMMAP EVLGALNPLH AVLFFVRDGW SGFQVLGAVF LVVTGGEALY
     ADMGHFGRLP IRLAWFCCVL PALLLNYFGQ GALLLSDPSE ATEPFYHLAP PWALYPLVLL
     ATLATIIASQ AVISGVFSLT RQAIQLRLSP RMRIVQTSSE EIGQIYIPAV NWALMLATIT
     LVAGFGSSSG LAAAYGVAVA TTMVITALLV RFVMLERWHW HPLAVAGLTV VFLTVDLAFF
     GANILKVGAG GWIPLAAGLA VFTVMITWRR GRELVTTHLL AQATPLPSFL EELAAKPPQR
     VPGTAVFMSG RLFPAPPTLI HHLEHNKVLH EQVVILTVLT EDIPRVSASE RIELKRLGQG
     FYRLIVRYGF MQSPNVPVIL RECEPLGLVT DPETTTFYLG RETLIPTEKV SGMPHWREKL
     FAFMSRNSLQ ATAFYNLPPD RVVELGQQVE I