ID   KUP1_LEGPA              Reviewed;         624 AA.
AC   Q5X5Y0;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable potassium transport system protein kup 1 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup1 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=lpp1190;
OS   Legionella pneumophila (strain Paris).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=297246;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Paris;
RX   PubMed=15467720; DOI=10.1038/ng1447;
RA   Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L.,
RA   Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J.,
RA   Glaser P., Buchrieser C.;
RT   "Evidence in the Legionella pneumophila genome for exploitation of host
RT   cell functions and high genome plasticity.";
RL   Nat. Genet. 36:1165-1173(2004).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CR628336; CAH12341.1; -; Genomic_DNA.
DR   RefSeq; WP_011213541.1; NC_006368.1.
DR   AlphaFoldDB; Q5X5Y0; -.
DR   KEGG; lpp:lpp1190; -.
DR   LegioList; lpp1190; -.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   OMA; AIRVSWL; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..624
FT                   /note="Probable potassium transport system protein kup 1"
FT                   /id="PRO_0000209029"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   624 AA;  69942 MW;  5293CBECBABB8E9A CRC64;
     MKKNRFTYGL ALGALGIVFG DIGTSPLYAL KVTLSGIPIN QFNILGVLSL IFWSLIIVVS
     FKYLMIIFRA DNDGEGGILA LLALMKHKST KYQPVFYIVA IFGAGLLLGD GMLTPAISVV
     SAVEGLGTLS DKLYPYVLPI ASLILVLLFS LQAKGTARIG YLFGPLILIW FITIAILGIL
     QILEHPVVLK AINPYYAIAF LVDEGLRGYF LLGGIFLVVT GGEALFADIG HFGKNPIRFS
     WFFIALPCLL LNYFGQGANL IVRPEEISNP FFMIAPPWFY LPLIIIATVA TVIASQAVIS
     ATFSLTKQAV LLGLCPKIPI VQTSMLHSGQ IYVPQINFIL FIGTMAFCLA FKTSDNLAHA
     YGIAVNLEML LVDAMVAYAA VSIWRWSTFN VIFLFGLFLL IDLAFLGANT HKFITGGWVP
     IVLAFFIAFI MYSWRYGLEY LRDNFYMNKE DISKILKQLQ YKSLNQLPGV SAIFITDVYD
     KSGGSFLHFL KLNRSVPENV LIVNYIVDNI PYVHYSQRYE IVCLDEKVCK LVIHYGFMET
     INIPRSLEKA CNKNILPFKF NVDTATFMVE IPNIMASKEK RSLSFYWQEK LFAFLMRNYS
     ANLNIEFYKL PYNRTIAIGT YCIL