ID   KUP1_LEGPH              Reviewed;         624 AA.
AC   Q5ZW98;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Probable potassium transport system protein kup 1 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup1 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=lpg1188;
OS   Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS   33152 / DSM 7513).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=272624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513;
RX   PubMed=15448271; DOI=10.1126/science.1099776;
RA   Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA   Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA   Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA   Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA   Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA   Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA   Russo J.J.;
RT   "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL   Science 305:1966-1968(2004).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAU27273.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE017354; AAU27273.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_050070678.1; NC_002942.5.
DR   RefSeq; YP_095220.1; NC_002942.5.
DR   AlphaFoldDB; Q5ZW98; -.
DR   STRING; 272624.lpg1188; -.
DR   PaxDb; Q5ZW98; -.
DR   EnsemblBacteria; AAU27273; AAU27273; lpg1188.
DR   GeneID; 66490366; -.
DR   KEGG; lpn:lpg1188; -.
DR   PATRIC; fig|272624.6.peg.1250; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   Proteomes; UP000000609; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..624
FT                   /note="Probable potassium transport system protein kup 1"
FT                   /id="PRO_0000209032"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   624 AA;  69902 MW;  3832E6D557A428DF CRC64;
     MKKNRFTYGL ALGALGVVFG DIGTSPLYAL KVTLSGIPIN QFNILGVLSL IFWSLIIIVS
     FKYLMIIFRA DNDGEGGILA LLALMKHKST KYQPLFYIVA IFGAGLLLGD GMLTPAISVV
     SAVEGLGTLS DKLYPYVLPI ASVILVLLFS LQAKGTARIG YLFGPLILIW FITIAILGIL
     QIVEHPVVLQ AINPYHAIAF LVDEGLRGYF LLGGIFLVVT GGEALFADIG HFGKNPIRFS
     WFFIALPCLL LNYFGQGANL IVRPEEISNP FFMIAPPWFY LPLIIIATVA TVIASQAVIS
     ATFSLTKQAV LLGLCPKIPI VQTSMLHSGQ IYVPQINFIL FIGTMAFCLA FKTSDNLAHA
     YGIAVNLEML LVDAMVAYAA VSIWRWSTFN VIFLFGLFLL IDLAFLGANT HKFITGGWVP
     IVLAFFIAFI MYSWRYGLEY LRDNFYMNKE DISKILKQLQ YKSLNQLPGV SAIFITDVYD
     KSGGSFLHFL KLNRSVPENV LIVNYIVDNI PYVHYSQRYE IVCLDEKVCK LVIHYGFMET
     INIPRSLEKA CNKNILPFKF NVDTATFMVE IPNIMASKEK RSLSFYWQEK LFAFLMRNYS
     ANLNIEFYKL PYNRTIAIGT YCIL