ID   KUP1_LEGPL              Reviewed;         624 AA.
AC   Q5WXA2;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable potassium transport system protein kup 1 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup1 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=lpl1196;
OS   Legionella pneumophila (strain Lens).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=297245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lens;
RX   PubMed=15467720; DOI=10.1038/ng1447;
RA   Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L.,
RA   Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J.,
RA   Glaser P., Buchrieser C.;
RT   "Evidence in the Legionella pneumophila genome for exploitation of host
RT   cell functions and high genome plasticity.";
RL   Nat. Genet. 36:1165-1173(2004).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CR628337; CAH15435.1; -; Genomic_DNA.
DR   RefSeq; WP_011215289.1; NC_006369.1.
DR   AlphaFoldDB; Q5WXA2; -.
DR   EnsemblBacteria; CAH15435; CAH15435; lpl1196.
DR   KEGG; lpf:lpl1196; -.
DR   LegioList; lpl1196; -.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   OMA; AIRVSWL; -.
DR   Proteomes; UP000002517; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..624
FT                   /note="Probable potassium transport system protein kup 1"
FT                   /id="PRO_0000209035"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   624 AA;  69717 MW;  3BF3347F22907C78 CRC64;
     MKKNRFTYGL ALGALGVVFG DIGTSPLYAL KVTLSGIPIN QFNILGVLSL IFWSLIIVVS
     FKYLMIIFRA DNNGEGGILA LLALMKHKST KYQPLFYIVA IFGAGLLLGD GMLTPAISVV
     SAVEGLGTLS DKLYPYVLPI ASLILILLFS LQATGTGRIG YLFGPLILVW FITIAILGIL
     QIAEHPVVLK AINPYYAIAF LVDEGLQGYL LLGGIFLVVT GGEALFADIG HFGKNPIRFS
     WFFAALPCLL LNYFGQGANL IVRPEAISNP FFMIAPSWFY LPLIIIATVA TVIASQAVIT
     ATFSLTKQAV LLGLCPKIPI VQTSMLHSGQ IYVPQINFIL FIGTMAFCLA FKTSDNLAHA
     YGIAVNLEML LVDAMVAYAA ISIWRWSIFN VMFLFGLFLL IDLAFLGANT HKFITGGWVP
     IVLAFFIAFI MYSWRYGLEY LRDNFYMNKE DISKILKQLQ YKSLNQLPGV SAIFITDVYD
     KSGGSFLHFL KLSRSVPENV LIVNYIVDNI PYVHYSQRYE IVCLDEKVCK LVIHYGFMET
     INIPRSLEKA CNKNILPFKF NVDTATFMVE IPNIMASKEK RSLSFYWQEK LFAFLMRNYS
     ANLNIEFYKL PYNRTIAIGT YCIL