ID   KUP1_POLSJ              Reviewed;         641 AA.
AC   Q123Z8;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable potassium transport system protein kup 1 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup1 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Bpro_4252;
OS   Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas; unclassified Polaromonas.
OX   NCBI_TaxID=296591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS666 / ATCC BAA-500;
RX   PubMed=18723656; DOI=10.1128/aem.00197-08;
RA   Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA   Stothard P., Coleman N.V.;
RT   "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT   a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT   relevance to biotechnology.";
RL   Appl. Environ. Microbiol. 74:6405-6416(2008).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000316; ABE46144.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q123Z8; -.
DR   STRING; 296591.Bpro_4252; -.
DR   EnsemblBacteria; ABE46144; ABE46144; Bpro_4252.
DR   KEGG; pol:Bpro_4252; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_4; -.
DR   OMA; GHETIIP; -.
DR   Proteomes; UP000001983; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..641
FT                   /note="Probable potassium transport system protein kup 1"
FT                   /id="PRO_0000279808"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        299..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        385..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        438..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   641 AA;  69317 MW;  C14C0FD74871DDE2 CRC64;
     MRVRRQCSPV LHRSLSMNQI SQRQGVAALT LGAIGVVYGD IGTSPLYTMK EIFSPATGIP
     LDATHLIGAV SVIFWGLMMI VTLKYVVLIL RASNRGEGGI MALTALAAHA AGKTPGRRTA
     LLLTGVLGAA LFYGDSVITP AISVLSAVEG LEVVAPGLKP YVLPVSLAVL VGLFMVQRHG
     TGVVGKLFGP VIVLWFAVLA FTGVVQILQQ PAILAALNPL RAVAFLHAQG WHLFVAVGAI
     VLAFTGVEAL YADMGHFGKR PIQLAWMGLV LPALALNYMG QGALLMRDPS ALENPFYRLF
     PQAWLIPAVI LATCATVIAS QAVISGAYSM TKQAVQLGLL PRMQVQYTSA REAGQIYMPE
     VNWILLAAVL LAVVGFGSSS ALAAAYGIAV TMTMLITTVL TFFVVRHGWG YPLPVALAAT
     GVFLALDTVL VIACSLKFWQ GGWFPLVLGV VLFILMATWK RGRELLIENI RNNDPELLPF
     ISSLAKDSMH RTPRTAVYAV ANPDTVPQAL LHNLKHNQVI HERNLILTVV FHEVPWIPFE
     ERVQVTPLVP GFWKVQVNYG FKNTPDVPQA LELCRDQGLA LNLFETSYFL SRETIVPTKG
     AGMTHWREAL FAAMSRNAGS VVGFLRLPNN SVIELGTRVQ I