KUP2_AGRFC
ID KUP2_AGRFC Reviewed; 637 AA.
AC Q8UJL0; Q7D304;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 2.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Atu5466;
GN ORFNames=AGR_pAT_688;
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OG Plasmid AT.
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01522}.
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR EMBL; AE007872; AAK90841.2; -; Genomic_DNA.
DR PIR; AC3217; AC3217.
DR RefSeq; NP_396400.2; NC_003064.2.
DR RefSeq; WP_010974698.1; NC_003064.2.
DR AlphaFoldDB; Q8UJL0; -.
DR STRING; 176299.Atu5466; -.
DR EnsemblBacteria; AAK90841; AAK90841; Atu5466.
DR KEGG; atu:Atu5466; -.
DR PATRIC; fig|176299.10.peg.5138; -.
DR eggNOG; COG3158; Bacteria.
DR HOGENOM; CLU_008142_4_2_5; -.
DR OMA; FDTCMVT; -.
DR PhylomeDB; Q8UJL0; -.
DR BioCyc; AGRO:ATU5466-MON; -.
DR Proteomes; UP000000813; Plasmid At.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01522; Kup; 1.
DR InterPro; IPR003855; K+_transporter.
DR InterPro; IPR023051; K+_uptake_low_affin.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Plasmid;
KW Potassium; Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..637
FT /note="Probable potassium transport system protein kup 2"
FT /id="PRO_0000208989"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT TRANSMEM 429..449
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ SEQUENCE 637 AA; 69506 MW; E4B2BE2745DAA327 CRC64;
MTSSNSTVPD SRSETKKFLV LLLGSIGVVY GDIGTSPLYA FRESLRPFTA NGVQHEHVVG
LISLMIWTLT IIVTFKYVLF LLRADNDGEG GTLSLLALLM KKTGSYMPVL FFAGLIGSAL
FIGDAMITPA LSVMSALEGM KLVTPAFSDY VLPLSALIMV GLFAVQSKGT GAVAVFFGPI
TVVWFLAMAW GGLIHIGDDW TILEAVNPIN ALWFITHAGW AGLIVLGAVF LTVTGAEALY
ADLGHFGRKP ISVAWFILVF PALALNYLGQ GALVLSNPAA IENPFYLLYP EWALFPMIIL
ATMATVIASQ AVITGAFSLA RQAVHLGFLP KLMIRFTSET NTGQIYVPAV NMVLFIGVLV
LIFSFGDSES LATAYGISVT GAMVVTTLMA FQFLRSIRGK SAFTAAILLA PLFSIEAVFL
AANLLKVHDG GWVPLALAGV IILVMWTWTK GSRYLREKIS KNDVSLDTFI TSLERSISRE
SRSAPVLVSG TAVFLTSVPD KAPSVLLHNL KHNHVLHEQN VILTIWTHDK PYVADTDRVE
ITRISKHFMR LDINFGFMDD PNVVKALPLC KKKGFKFEIM QTSFYLGRRN LIATPNTGLP
RWQEDLYIAL ADFGVDPSAY FKLPPNRVIE IGEQVAI
