ID   KUP2_GEOMG              Reviewed;         606 AA.
AC   Q39ZN5;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Gmet_0039;
OS   Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=269799;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53774 / DSM 7210 / GS-15;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Geobacter metallireducens GS-15.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000148; ABB30289.1; -; Genomic_DNA.
DR   RefSeq; WP_004513806.1; NC_007517.1.
DR   AlphaFoldDB; Q39ZN5; -.
DR   STRING; 269799.Gmet_0039; -.
DR   PRIDE; Q39ZN5; -.
DR   EnsemblBacteria; ABB30289; ABB30289; Gmet_0039.
DR   KEGG; gme:Gmet_0039; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_7; -.
DR   OMA; LMIMCIV; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000007073; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..606
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_0000279787"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        418..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   606 AA;  66611 MW;  E0F9C672FADA6762 CRC64;
     MVQEHTESFW GGIIKSMGLV FGDIGTSPIY TLTVIMTLTK PDAEHVLGIL SLIVWTLIIL
     VSVEYAWLAM SLGRKGEGGT IVLKEILVRL LKSGRQVAFV GFLAFMGVSL LLGDGIITPA
     ISILSAVEGM RLIPGWENLA QGVLIFIAAV IALILFIFQF KGTDKVAGAF GPIMVIWFGA
     LTLSGIVSIA GTPEVVSAVS PHHAVTFLMH NGLAGFFILS EVILCATGGE ALYADMGHLG
     RKPIIRAWYF VFSALVINYL GQGAFILRNP NETNILFSMV KSQAPILYIP FLCLTIMATI
     IASQALISGV FSIVYQGITT RILPLMKVDY TSTHLKSQIY IGSVNWSLLV AVIFIMLIFK
     KSENLAAAYG LAVTGTMFIT GIMMTMIFSH TTKKWKVPIA LAVTLIDLVY LTANFHKLPH
     GGYWSLILAS IPLAIMIIWT QGQKALYRAL RPLDLDTFLL SFGQIYAKGH NIPGTGLFFV
     RETAVVPPYV IHCIIRSNII YERNVFVSLN RSDEPFGVKA NLTKGIGPGL DSFEILAGYM
     ELVDIERLLK KKGIEEKVIF YGIEDIATNN PFWRVFSTIK RQTANFVQFN KLPVSKLQGV
     VTRVEM