ID   KUP2_GEOSL              Reviewed;         605 AA.
AC   Q74AA5;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=GSU2485;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE017180; AAR35858.1; -; Genomic_DNA.
DR   RefSeq; NP_953531.1; NC_002939.5.
DR   RefSeq; WP_010943122.1; NC_002939.5.
DR   AlphaFoldDB; Q74AA5; -.
DR   STRING; 243231.GSU2485; -.
DR   EnsemblBacteria; AAR35858; AAR35858; GSU2485.
DR   KEGG; gsu:GSU2485; -.
DR   PATRIC; fig|243231.5.peg.2511; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_7; -.
DR   InParanoid; Q74AA5; -.
DR   OMA; VKYICIA; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..605
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_0000209017"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        367..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        394..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        417..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   605 AA;  66673 MW;  57DD169F176F2824 CRC64;
     MKTEAQSYWG GIIKSMGLVF GDIGTSPIYT LTVIMTLTKP DAEHVLGILS LIVWTLIILV
     TVEYAWLAMS LGRKGEGGTI VLKEILIRLL KSGRQMAFAG FLAFLGVSLL LGDGVITPAI
     SILSAVEGMR LIPGLEDLAQ GGLILVAAVI AVFLFIFQFK GTDKVASAFG PIMVVWFSAL
     TVSGLVSIIG TPTVVQAISP HHAVLFLKHN GLAGFFVLSE VILCATGGEA LYADMGHLGR
     KPIIRAWYFV FCALVINYLG QGAFILRNPE AKNILFSMVK SQVPMLYIPF LLLTISATII
     ASQALISGVF SIVYQGITTR ILPLMKVDYT STHLKSQIYI GSVNWSLLVA VIFIMILFQR
     SENLAAAYGL AVTGTMFITG IMMTMIFSRT TKKWKVPIAL AVTVIDFAYL TANLHKLPHG
     GYWSLVLASI PLAIMVIWTR GQRALYRSLK PLDLDTFLLS YEQIYAKGHN IPGTGLFFVR
     ETPVVPPYVI HCIIRSNIIY ERNVFVSLTR TDEPFDVRTK LTRGIGTGLD AFEVNAGYME
     RLDIEKLLKK HGVEEKVIFY GIEDIDTSNP VWRIFATIKR QSANFVQFNK LPVSKLQGVV
     TRVEM