ID   KUP2_LEGPL              Reviewed;         624 AA.
AC   Q5WUW3;
DT   01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=lpl2054;
OS   Legionella pneumophila (strain Lens).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=297245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lens;
RX   PubMed=15467720; DOI=10.1038/ng1447;
RA   Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L.,
RA   Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J.,
RA   Glaser P., Buchrieser C.;
RT   "Evidence in the Legionella pneumophila genome for exploitation of host
RT   cell functions and high genome plasticity.";
RL   Nat. Genet. 36:1165-1173(2004).
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CR628337; CAH16294.1; -; Genomic_DNA.
DR   RefSeq; WP_011216034.1; NC_006369.1.
DR   AlphaFoldDB; Q5WUW3; -.
DR   EnsemblBacteria; CAH16294; CAH16294; lpl2054.
DR   KEGG; lpf:lpl2054; -.
DR   LegioList; lpl2054; -.
DR   HOGENOM; CLU_008142_4_2_6; -.
DR   OMA; GHETIIP; -.
DR   Proteomes; UP000002517; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..624
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_0000209036"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        335..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        364..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        416..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   624 AA;  70766 MW;  4E590F04C8D4DE35 CRC64;
     MNESLTEKRN ELSLSFAALG VVFGDIGTSP LYAFGQVIKY FPINDYNIYG ILSLIFWSLI
     IIVSIKYLVI VFRADNDGEG GIIALAGVIR QKIKKPGGWL LFITLVGIGL IIGDGMLTPA
     ISILSAVEGL ESLSPNLAKY VLPVTLIILF FLFKMQSIGT GKIGVYFAPV MLVWFITIGI
     LGFLQIIQNP KVLMAINPYY AINFFMIHQY SALFILGGVF LVMTGGEALF ADLGHFGKKA
     IRTGWFAVAL PALLLCYFGQ GAFVLMHTED IKYPFFSLSP DWFLPVMIIL ATLATIIASQ
     AIISAAFSIL KQASLLNLIP RLKIVFTSKF EKGEVYLPLI NFILALGTCS LVVIFKSSSN
     LADAYGIAVN LDMLITTVLV GIIAYRCWSW HAFKILIFLL ILIIELAFFA GNIPKLLTGG
     WIPVLIAFLG FVVMYTWHCG FEKLRELHHR DALMDAFIID ELNQNKISRQ PGMGLYIIDP
     YDYEGESLLH HLRLNRIFFE NMVFVSIKIE NKPYIPIEDK FELIKKAEGF YLIFIHYGFT
     ENINLPNELD EMFKRVYLPF DIIKNKLIYF IEIVFVEMTG ERQKHMYLWQ KHFFSLMIRN
     AVPDIQFYQL PYNNTIAIGT YYQF