ID   KUP2_NOVAD              Reviewed;         634 AA.
AC   Q2G870;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable potassium transport system protein kup 2 {ECO:0000255|HAMAP-Rule:MF_01522};
GN   Name=kup2 {ECO:0000255|HAMAP-Rule:MF_01522}; OrderedLocusNames=Saro_1512;
OS   Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG
OS   56034 / CIP 105152 / NBRC 16084 / F199).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=279238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 /
RC   F199;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N.,
RA   Fredrickson J., Balkwill D., Romine M.F., Richardson P.;
RT   "Complete sequence of Novosphingobium aromaticivorans DSM 12444.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transport of potassium into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01522}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01522}.
CC   -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
CC       {ECO:0000255|HAMAP-Rule:MF_01522}.
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DR   EMBL; CP000248; ABD25953.1; -; Genomic_DNA.
DR   RefSeq; WP_011445165.1; NC_007794.1.
DR   AlphaFoldDB; Q2G870; -.
DR   STRING; 279238.Saro_1512; -.
DR   EnsemblBacteria; ABD25953; ABD25953; Saro_1512.
DR   KEGG; nar:Saro_1512; -.
DR   eggNOG; COG3158; Bacteria.
DR   HOGENOM; CLU_008142_4_2_5; -.
DR   OMA; AADQFEI; -.
DR   OrthoDB; 589903at2; -.
DR   Proteomes; UP000009134; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01522; Kup; 1.
DR   InterPro; IPR003855; K+_transporter.
DR   InterPro; IPR023051; K+_uptake_low_affin.
DR   PANTHER; PTHR30540; PTHR30540; 1.
DR   Pfam; PF02705; K_trans; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW   Potassium transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..634
FT                   /note="Probable potassium transport system protein kup 2"
FT                   /id="PRO_5000106186"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        381..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        408..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
FT   TRANSMEM        435..455
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01522"
SQ   SEQUENCE   634 AA;  67725 MW;  6889DA4340D86EC6 CRC64;
     MQTITRTSRN SLASLTLGAI GVVYGDIGTS PLYAFREALG QAARDGIVQA EIVGVLSLAL
     WALIIVVTLK YVIFLSRMDN NGEGGVLSLM ALAQRATGGG WVAVTLLGAT GAALFYGDAI
     ITPALSVLSA AEGLKTIPGL DGMSQTAIIG VTVGILAALF MFQSRGTASV ATLFGPVCLV
     WFVALAGLGL WHIADAPEVL TAFNPLHAVT FLVSHGVTGL FVLGAVFLTV TGAEALIADM
     GHFGRRPIQL GWLSFVWPAL TLNYLGQGAL ALKALAAAEA IGQPLANADW FFIMAPDVLR
     APLVILATLA TIIASQAVIT GAYSLTHQAI SLGLLPRLTI RQTSEHQMGQ IYMPGVNWLL
     LGGVLLLVLG FKSSSAMAAA YGIAVTGTMV VTTCMAFLIA WKYWNWEPVW TALLIAPFLA
     LDLFFFGANI LRVSEGGWVP LLVAGLVGLV IFTWLKGRRT ALARASEQGV SLNETVMALH
     ARPPTRIEGT AVFLTQDLDV TPSALLHNLK HNKALHRNNI VLKVEIQARP YVAPEQRVVV
     DRIDESFLKA RLRYGYMDTI DVPSDLARAD GLLVGPGGTS FFVGRSAIRF AARPVLPRWM
     TVVYMFLHRN AADPTAYFSI PSNRVVELGS QIEL